Semiconductor quantum dot toxicity in a mouse in vivo model

Quantum dots (QDs) are increasingly widely used in clinical medicine. Their most promising potential applications are cancer diagnosis, including in vivo tumour imaging and targeted drug delivery. In this connection, the main questions are whether or not QDs are toxic for humans and, if they are, wh...

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Bibliographic Details
Published in:Journal of physics. Conference series 2017-01, Vol.784 (1), p.12013
Main Authors: Bozrova, Svetlana V, Baryshnikova, Maria A, Nabiev, Igor, Sukhanova, Alyona
Format: Article
Language:English
Subjects:
Biocompatibility
Bioengineering
Cadmium selenides
Clinical medicine
Electrons
Engineering Sciences
Fluorescence
Imaging
Life Sciences
Micro and nanotechnologies
Microelectronics
Physics
Quantum dots
Toxicity
Toxicology
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Summary:Quantum dots (QDs) are increasingly widely used in clinical medicine. Their most promising potential applications are cancer diagnosis, including in vivo tumour imaging and targeted drug delivery. In this connection, the main questions are whether or not QDs are toxic for humans and, if they are, what concentration is relatively harmless. We have carried out in vivo experiments with CdSe/ZnS fluorescent semiconductor core/shell QDs, which are currently the most widely used in research.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/784/1/012013