Guest Exchange by a Partial Energy Ratchet in Water

Molecular machines are ubiquitous in nature and function away from equilibrium by consuming fuels to produce appropriate work. Chemists have recently excelled at mimicking the fantastic job performed by natural molecular machines with synthetic systems soluble in organic solvents. In efforts toward...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 2021-03, Vol.60 (12), p.6617-6623
Main Authors: Yang, Xue, Cheng, Qian, Monnier, Valerie, Charles, Laurence, Karoui, Hakim, Ouari, Olivier, Gigmes, Didier, Wang, Ruibing, Kermagoret, Anthony, Bardelang, David
Format: Article
Language:English
Subjects:
Alginates
Alginic acid
Chemical Sciences
Chemists
cucurbituril
Exchanging
Fluorescence
host–guest interactions
Hydrogels
Mimicry
Molecular machines
Organic solvents
pH effects
ratchet
supramolecular chemistry
water
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Molecular machines are ubiquitous in nature and function away from equilibrium by consuming fuels to produce appropriate work. Chemists have recently excelled at mimicking the fantastic job performed by natural molecular machines with synthetic systems soluble in organic solvents. In efforts toward analogous systems working in water, we show that guest molecules can be exchanged in the synthetic macrocycle cucurbit[7]uril by involving kinetic traps, and in such a way as modulating energy wells and kinetic barriers using pH, light, and redox stimuli. Ditolyl‐viologen can also be exchanged using the best kinetic trap and interfaced with alginate, thus affording pH‐responsive blue, fluorescent hydrogels. With tunable rate and binding constants toward relevant guests, cucurbiturils may become excellent ring molecules for the construction of advanced molecular machines working in water. Cucurbiturils can be prime components to build energy ratchets in water. Guest molecules can be exchanged in the synthetic macrocycle cucurbit[7]uril by involving kinetic traps, and in such a way as modulating energy wells and kinetic barriers using pH, light, and redox stimuli.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.202014399