Regulating the regulator: nitric oxide control of post-translational modifications

Nitric oxide (NO) is perfectly suited for the role of a redox signalling molecule. Akey route for NO bioactivity occurs via protein S-nitrosation, and involves the addition of a NO moiety to a protein cysteine (Cys) thiol (–SH) to form an S-nitrosothiol (SNO). This process is thought to underpin a m...

Full description

Saved in:
Bibliographic Details
Published in:The New phytologist 2020-09, Vol.227 (5), p.1319-1325
Main Authors: Gupta, Kapuganti Jagadis, Kolbert, Zsuzsanna, Durner, Jorg, Lindermayr, Christian, Corpas, Francisco J., Brouquisse, Renaud, Barroso, Juan B., Umbreen, Saima, Palma, José M., Hancock, John T., Petrivalsky, Marek, Wendehenne, David, Loake, Gary J.
Format: Article
Language:English
Subjects:
Acetylation
Adaptation
Biological activity
Immune response
Life Sciences
Nitric oxide
nitric oxide (NO)
Nitric Oxide - metabolism
Nitrosation
Oxidation-Reduction
Oxidoreductions
persulfidation
Phosphorylation
Plants - metabolism
Protein Processing, Post-Translational
Protein S
Proteins
reactive nitrogen species (RNS)
reactive oxygen species (ROS)
S-Nitrosothiols
SUMO protein
SUMOylation
S‐nitrosation
S‐nitrosylation
Tansley insight
Translation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nitric oxide (NO) is perfectly suited for the role of a redox signalling molecule. Akey route for NO bioactivity occurs via protein S-nitrosation, and involves the addition of a NO moiety to a protein cysteine (Cys) thiol (–SH) to form an S-nitrosothiol (SNO). This process is thought to underpin a myriad of cellular processes in plants that are linked to development, environmental responses and immune function. Here we collate emerging evidence showing that NO bioactivity regulates a growing number of diverse post-translational modifications including SUMOylation, phosphorylation, persulfidation and acetylation. We provide examples of how NO orchestrates these processes to mediate plant adaptation to a variety of cellular cues.
ISSN:0028-646X
1469-8137
DOI:10.1111/nph.16622