Optimizing sample illumination scanning in transmission tomographic diffractive microscopy

Due to the sequential nature of data acquisition, it is preferable to limit the number of illuminations to be used in tomographic diffractive microscopy experiments, especially if fast imaging is foreseen. On the other hand, for high-quality, high-resolution imaging, the Fourier space has to be opti...

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Bibliographic Details
Published in:Applied optics (2004) 2021-02, Vol.60 (6), p.1694
Main Authors: Taddese, Asemare Mengistie, Verrier, Nicolas, Debailleul, Matthieu, Courbot, Jean-Baptiste, Haeberlé, Olivier
Format: Article
Language:English
Subjects:
Comparative studies
Engineering Sciences
Illumination
Image quality
Image resolution
Microscopy
Optical transfer function
Optics
Optimization
Photonic
Scanning
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Summary:Due to the sequential nature of data acquisition, it is preferable to limit the number of illuminations to be used in tomographic diffractive microscopy experiments, especially if fast imaging is foreseen. On the other hand, for high-quality, high-resolution imaging, the Fourier space has to be optimally filled. Up to now, the problem of optimal Fourier space filling has not been investigated in itself. In this paper, we perform a comparative study to analyze the effect of sample scanning patterns on Fourier space filling for a transmission setup. Optical transfer functions for several illumination patterns are studied. Simulation as well as experiments are conducted to compare associated image reconstructions. We found that 3D uniform angular sweeping best fills the Fourier space, leading to better quality images.
ISSN:1559-128X
2155-3165
DOI:10.1364/AO.417061