Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus

Background Few pharmacokinetic data were reported on dispersible tablets despite their increasing use. One hundred fifty HIV-infected children receiving lamivudine were enrolled in the MONOD ANRS 12,206 trial. Three galenic forms were administered: liquid formulation, tablet form and dispersible sco...

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Bibliographic Details
Published in:Antiviral therapy 2021-11, Vol.26 (6-8), p.134-140
Main Authors: Pressiat, Claire, Dainguy, Evelyne, Tréluyer, Jean-Marc, Yonaba, Caroline, Urien, Saik, Eboua, François, Foissac, Frantz, Dahourou, Désiré Lucien, Bouazza, Naïm, Malateste, Karen, Desmonde, Sophie, Pruvost, Alain, Leroy, Valériane, Hirt, Déborah, Study Group, The MONOD ANRS
Format: Article
Language:English
Subjects:
Anti-HIV Agents - pharmacokinetics
Anti-HIV Agents - therapeutic use
Child
Child, Preschool
Children
Efavirenz
HIV
HIV Infections - drug therapy
HIV-1
Human immunodeficiency virus
Humans
Lamivudine
Lamivudine - pharmacokinetics
Lamivudine - therapeutic use
Life Sciences
Lopinavir
Pharmacokinetics
Santé publique et épidémiologie
Syrups
Tablets - therapeutic use
Zidovudine
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Summary:Background Few pharmacokinetic data were reported on dispersible tablets despite their increasing use. One hundred fifty HIV-infected children receiving lamivudine were enrolled in the MONOD ANRS 12,206 trial. Three galenic forms were administered: liquid formulation, tablet form and dispersible scored tablet. Method HIV-infected children
ISSN:1359-6535
2040-2058
DOI:10.1177/13596535211058267