First case of Elizabethkingia anophelis meningitis in the Central African Republic

The isolate was, however, susceptible to moxifloxacin. Because parenteral pipericillin and moxifloxacin were not available in our setting, antimicrobial treatment was changed to ampicillin and gentamicin on day 5, and the fever resolved by day 9. The bacterium in this patient was resistant to most a...

Full description

Saved in:
Bibliographic Details
Published in:The Lancet (British edition) 2013-05, Vol.381 (9880), p.1876-1876
Main Authors: Frank, Thierry, PhD, Gody, Jean Chrysostome, MD, Nguyen, Liem Binh Luong, MD, Berthet, Nicolas, PhD, Fleche-Mateos, Anne Le, PhD, Bata, Petula, MD, Rafaï, Clotaire, MD, Kazanji, Mirdad, PhD, Breurec, Sebastien, PhD
Format: Article
Language:English
Subjects:
Animals
Anopheles - microbiology
Antibiotics
Biological and medical sciences
Central African Republic
Female
Flavobacteriaceae Infections - diagnosis
General aspects
Human health and pathology
Humans
Infant, Newborn
Infections
Internal Medicine
Life Sciences
Medical sciences
Meningitis
Meningitis, Bacterial - diagnosis
Meningitis, Bacterial - microbiology
Nosocomial infection
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The isolate was, however, susceptible to moxifloxacin. Because parenteral pipericillin and moxifloxacin were not available in our setting, antimicrobial treatment was changed to ampicillin and gentamicin on day 5, and the fever resolved by day 9. The bacterium in this patient was resistant to most antibiotics that are recommended as empirical antibiotic therapy for neonatal meningitis,4 which probably accounts for the poor outcomes in this and the previous case.2 Prompt, appropriate antibiotic therapy is the cornerstone of treatment of meningitis.4 Outbreaks due to Elizabethkingia spp could pose a serious health problem because of the lack of measures to prevent nosocomial infections in many African hospitals, high rates of resistance to antibiotics,1 and the shortage of effective parenteral antibiotics.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(13)60318-9