Experimental evolution with Drosophila

Department of Ecology and Evolutionary Biology, University of California, Irvine, California Submitted 30 June 2008 ; accepted in final form 25 March 2009 ABSTRACT Experimental evolution is a powerful approach that can be used for the study of adaptation. Evolutionary biologists often use Drosophila...

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Bibliographic Details
Published in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2009-06, Vol.296 (6), p.R1847-R1854
Main Authors: Burke, Molly K, Rose, Michael R
Format: Article
Language:English
Subjects:
Adaptation, Physiological - genetics
Animals
Drosophila - genetics
Drosophila - metabolism
Drosophila Proteins - genetics
Drosophila Proteins - metabolism
Entomology
Evolution
Evolution, Molecular
Evolutionary biology
Experiments
Genomics
Insects
Longevity - genetics
Models, Animal
Models, Genetic
Reproducibility of Results
Selection, Genetic
Stress, Physiological - genetics
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Summary:Department of Ecology and Evolutionary Biology, University of California, Irvine, California Submitted 30 June 2008 ; accepted in final form 25 March 2009 ABSTRACT Experimental evolution is a powerful approach that can be used for the study of adaptation. Evolutionary biologists often use Drosophila as a model organism in experiments that test theories about the evolution of traits related to fitness. Such evolution experiments can take three forms: direct selection for a trait of interest; surveys of traits of interest in populations selected for other traits; and reverse selection. We review some of the Drosophila experiments that have provided insight into both the evolution of particular physiological traits and the correlations between physiological and life history traits, focusing on stress resistance. The most common artifacts that can obscure the results from evolution experiments are discussed. We also include a treatment of genomic technologies that are now available for the Drosophila model. The primary goal of this review is to introduce the kind of experimental evolution strategies and technologies that evolutionary physiologists might use in the future. correlations; Drosophila ; laboratory evolution; physiology; stress resistance Address for reprint requests and other correspondence: M. K. Burke, Dept. of Ecology and Evolutionary Biology, Univ. of California, Irvine, CA 92617-2525 (e-mail: burkem{at}uci.edu )
ISSN:0363-6119
1522-1490
DOI:10.1152/ajpregu.90551.2008