Pulse oximetry: an improved in vitro model that reduces blood flow-related artifacts

Artifacts may occur in many in vitro models of pulse oximetry due to the optical effects of synchronously oriented and/or deformed erythrocytes. Although these artifacts are most likely negligible in living superficial tissues, they are demonstrated to have considerable influence on the calibration...

Full description

Saved in:
Bibliographic Details
Published in:IEEE transactions on biomedical engineering 2000-03, Vol.47 (3), p.338-343
Main Authors: Edrich, T., Flaig, M., Knitza, R., Rall, G.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood
Blood flow
Blood Flow Velocity
Calibration
Cardiovascular system
Cells
Computer simulation
Deformable models
Electromagnetic wave absorption
Hemoglobin oxygen saturation
Hospitals
In vitro
In vivo
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Mathematical models
Medical sciences
Models, Cardiovascular
Noninvasive medical procedures
Optical pulses
Optical saturation
Oximetry - methods
Oxygen
Physiology
Pulsatile Flow - physiology
Pulse measurements
Tissue
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Artifacts may occur in many in vitro models of pulse oximetry due to the optical effects of synchronously oriented and/or deformed erythrocytes. Although these artifacts are most likely negligible in living superficial tissues, they are demonstrated to have considerable influence on the calibration curve obtainable from the in vitro simulation of pulse oximetry in such models, especially at low oxygen saturations. Therefore, the authors have developed a modified in vitro model which reduces the effect of these artifacts. This is achieved by excluding data obtained during pressure transients and by raising the blood flow velocity. As a result, the model more closely approximates in vivo pulse oximetry, particularly under clinically important conditions of low blood oxygen saturation levels.
ISSN:0018-9294
1558-2531
DOI:10.1109/10.827294