3D Protoacoustic Imaging through a Planar Ultrasound Array: A Simulation Workflow

Bragg peak range uncertainties are a persistent constraint in proton therapy. Pulsed proton beams generate protoacoustic emissions proportional to absorbed proton energy, thereby encoding dosimetry information in a detectable acoustic wave. Here, we seek to derive and model 3D protoacoustic imaging...

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Bibliographic Details
Published in:IEEE transactions on radiation and plasma medical sciences 2022-05, p.1-1
Main Authors: Samant, Pratik, Trevisi, Luis M., Chen, Yong, Zwart, Townsend, Xiang, Liangzhong
Format: Article
Language:English
Subjects:
Acoustics
Analytical
Analytical dosimetry
Image guided therapy
Image guided therapy devices
Mathematical models
Particle beams
Protons
Radiation Therapy
Solid modeling
Three-dimensional displays
Transducers
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Summary:Bragg peak range uncertainties are a persistent constraint in proton therapy. Pulsed proton beams generate protoacoustic emissions proportional to absorbed proton energy, thereby encoding dosimetry information in a detectable acoustic wave. Here, we seek to derive and model 3D protoacoustic imaging with an ultrasound array and examine the frequency characteristics of protoacoustic emissions. A formalism is presented through which protoacoustic signals can be characterized considering transducer bandwidth as well as pulse duration of the incident beam. We have also collected an experimental proton beam intensity signal from a Mevion S250 clinical machine to analyze our formalism. We also show that proton-acoustic image reconstruction is possible even when the noise amplitude is larger than the signal amplitude on individual transducers. We find that a 4µs Gaussian proton pulse can generate a signal in the range of MHz as long as the spatial heating function has sufficiently high temperature gradients.
ISSN:2469-7311
2469-7303
DOI:10.1109/TRPMS.2022.3177236