Synthesis of New Chiral Aziridinoalcohols

Diasteromerically and enantiomerically pure aziridinoalcohols 4, 5, 6 and 7 were obtained from the reaction of racemic methyl 2, 3-dibromopropionate 1 with R and S-(2-phenylglycinol) 2 and 3 respectively. The products were separated via flash chromatography on silica gel in good yield.

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Bibliographic Details
Published in:Synthetic communications 2000-04, Vol.30 (7), p.1303-1309
Main Authors: Orea, L., Galindo, F. A., Gnecco, D., Toscano, R. A., Enriquez, R. G.
Format: Article
Language:English
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Summary:Diasteromerically and enantiomerically pure aziridinoalcohols 4, 5, 6 and 7 were obtained from the reaction of racemic methyl 2, 3-dibromopropionate 1 with R and S-(2-phenylglycinol) 2 and 3 respectively. The products were separated via flash chromatography on silica gel in good yield.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397910008087152