Metachronous Wilms Tumor Associated with Pulmonary Embolism: How Can We Detect These Cases Early? A Case Report and Literature Review

A 4-year-old girl developed right metachronous Wilms tumor 2 years after completing treatment for a left-sided stage I Wilms tumor. The original treatment included 7 weeks of chemotherapy, delayed nephrectomy, and another 3 weeks of chemotherapy. The metachronous tumor on the right side extended int...

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Bibliographic Details
Published in:Pediatric hematology and oncology 2003, Vol.20 (1), p.55-63
Main Authors: Ahmed, R., Al-Salti, W., Raafat, F., Morland, B.
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Child, Preschool
Female
Humans
Kidney Neoplasms - pathology
Kidney Neoplasms - surgery
Kidneys
Medical sciences
Metachronous Wilms Tumor
Neoplasms, Second Primary - complications
Neoplasms, Second Primary - diagnosis
Neoplasms, Second Primary - therapy
Nephrectomy
Nephrology. Urinary tract diseases
Pulmonary Embolism - etiology
Tumors of the urinary system
Wilms Tumor - complications
Wilms Tumor - diagnosis
Wilms Tumor - therapy
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Summary:A 4-year-old girl developed right metachronous Wilms tumor 2 years after completing treatment for a left-sided stage I Wilms tumor. The original treatment included 7 weeks of chemotherapy, delayed nephrectomy, and another 3 weeks of chemotherapy. The metachronous tumor on the right side extended into the inferior vena cava and right atrium. She developed pulmonary embolism as a result. She received chemotherapy and developed liquifaction of the tumor and toxic shock. She also had surgery. The patient is alive 3 years after the original diagnosis and 10 months after the relapse. The authors report this unusual case and discuss whether these cases can be identified early.
ISSN:0888-0018
1521-0669
DOI:10.1080/0888001390158559