Percutaneous Intragastric Catheter (PIC) for Administration of an Unpalatable Substance to Large Animals

We studied an easy and reliable technique for administration of an unpalatable substance to large animals. There were three groups of pigs: group I (n = 6) received 1 g ethanol/kg body weight per day orally with water for 24 days, group II (n = 6) received 2 g ethanol/kg orally with water for 24 day...

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Bibliographic Details
Published in:Journal of investigative surgery 2009-01, Vol.22 (2), p.122-128
Main Authors: Oleszczuk, Agnieszka, Spannbauer, Michael M., Blüher, Matthias, Ott, Rudolf, Pietsch, Uta-Carolin, Schneider, Katja, Madaj-Sterba, Petra, Fürll, Manfred, Hauss, Johann P., Schön, Michael R.
Format: Article
Language:English
Subjects:
Administration
Administration, Oral
Animals
Catheter
Catheterization - instrumentation
Catheterization - methods
Catheterization - veterinary
Ethanol
Ethanol - administration & dosage
Intragastric
Large animal
Method
Percutaneous
Pig
Stomach
Sus scrofa
Taste
Technique
Unpalatable
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Summary:We studied an easy and reliable technique for administration of an unpalatable substance to large animals. There were three groups of pigs: group I (n = 6) received 1 g ethanol/kg body weight per day orally with water for 24 days, group II (n = 6) received 2 g ethanol/kg orally with water for 24 days and 4 g ethanol/kg via percutaneous intragastric catheter (PIC) for the next 24 days, group III (n = 6) received 6 g ethanol/kg via PIC for 72 days. The catheter was placed after insufflation of the stomach using an orogastric tube. PIC was successfully placed in each pig. No complications occurred during placement. The total amount of the administrated dose was assimilated each time. PIC is a safe, effective, well tolerated, and precise method of administering ethanol that is inexpensive and easy to perform. Ethanol administration via PIC is a convenient and effective mean of exposing animals to high levels of alcohol on a long-term basis.
ISSN:0894-1939
1521-0553
DOI:10.1080/08941930802713050