HPLC Determination of Cilostazol in Tablets, and Its Validation

A simple, rapid, and validated HPLC method has been developed for determination of cilostazol in tablets. A LiChrospher 100 RP-18 column was used with a mobile phase consisting of methanol-acetonitrile-water (20:50:30). Quantitative evaluation was performed at 260 nm. The HPLC method is selective, p...

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Bibliographic Details
Published in:Journal of liquid chromatography & related technologies 2004-01, Vol.27 (16), p.2603-2612
Main Authors: Lestari, Ardhani Dwi, Palupi, Tini, Oktarina, Bertha, Yuwono, Mochammad, Indrayanto, Gunawan
Format: Article
Language:English
Subjects:
Analysis
Biological and medical sciences
Cilostazol
General pharmacology
HPLC
Medical sciences
Pharmacology. Drug treatments
Tablets
Validation
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Summary:A simple, rapid, and validated HPLC method has been developed for determination of cilostazol in tablets. A LiChrospher 100 RP-18 column was used with a mobile phase consisting of methanol-acetonitrile-water (20:50:30). Quantitative evaluation was performed at 260 nm. The HPLC method is selective, precise, and accurate, and it can be used for routine analysis of the preparations in pharmaceutical industry quality control laboratories.
ISSN:1082-6076
1520-572X
DOI:10.1081/JLC-200028425