Convenient Synthesis of Substituted 5-(Hydroxymethyl)-8-methyl-3-(4-phenylquinazolin-2-yl)-2H-pyrano[2,3-c]pyridin-2-ones

Interaction of 2-imino-2H-pyrano[2,3-c]pyridin-3-carboxamide with substituted 2-aminobenzophenones proceeds via recyclization mechanism leading to substituted 3-(4-arylquinazolyn-2-yl)-2H-pyrano[2,3-c]pyridin-2-ones. Their reaction with acetic anhydride affords the O-acylation products.

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Bibliographic Details
Published in:Synthetic communications 2005-01, Vol.35 (12), p.1641-1647
Main Authors: Zhuravel, Irina O., Kovalenko, Sergiy M., Ivachtchenko, Alexandre V., Chernykh, Valentin P., Shinkarenko, Pavlo E.
Format: Article
Language:English
Subjects:
2H-Pyrano[2,3-c]pyridin-2-one
quinazoline
recyclization
Online Access:Get full text
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Description
Summary:Interaction of 2-imino-2H-pyrano[2,3-c]pyridin-3-carboxamide with substituted 2-aminobenzophenones proceeds via recyclization mechanism leading to substituted 3-(4-arylquinazolyn-2-yl)-2H-pyrano[2,3-c]pyridin-2-ones. Their reaction with acetic anhydride affords the O-acylation products.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-200061638