Bioprinting by laser-induced forward transfer for tissue engineering applications: jet formation modeling

• Published in: Biofabrication 2010-03, Vol.2 (1), p.014103-014103
• Main Authors: Mézel, C, Souquet, A, Hallo, L, Guillemot, F
• Format: Article
• Language: English
• Subjects: Biotechnology - methods; Computer-Aided Design; Lasers; Tissue Engineering - methods
• ISSN: 1758-5090; 1758-5082; 1758-5090
• DOI: 10.1088/1758-5082/2/1/014103

In this paper, a nanosecond LIFT process is analyzed both from experimental and modeling points of view. Experimental results are first presented and compared to simple estimates obtained from physical analysis, i.e. energy balance, jump relations and analytical pocket dynamics. Then a self-consistent 2D axisymmetric modeling strategy is presented. It is shown that data accessible from experiments, i.e. jet diameter and velocity, can be reproduced. Moreover, some specific mechanisms involved in the rear-surface deformation and jet formation may be described by some scales of hydrodynamic process, i.e. shock waves propagation and expansion waves, as a consequence of the laser heating. It shows that the LIFT process is essentially driven by hydrodynamics and thermal transfer, and that a coupled approach including self-consistent laser energy deposition, heating by thermal conduction and specific models for matter is required.