Course and Clinical Significance of CD8⁺ T-Cell Counts in a Large Cohort of HIV-Infected Individuals

Objectives. To examine trajectories of CD8⁺ T-cell counts before and after combination antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-infected individuals and associations with mortality. Methods. CD8⁺ T-cell counts were measured in 3882 HIV-infected individuals who received car...

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Bibliographic Details
Published in:The Journal of infectious diseases 2015-06, Vol.211 (11), p.1726-1734
Main Authors: Helleberg, Marie, Kronborg, Gitte, Ullum, Henrik, Ryder, Lars P., Obel, Niels, Gerstoft, Jan
Format: Article
Language:English
Subjects:
Adult
Anti-Retroviral Agents - therapeutic use
CD4-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - immunology
Denmark - epidemiology
Female
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - immunology
HIV Infections - mortality
HIV/AIDS
Humans
Male
Middle Aged
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