Frontotemporal Dementia: A Randomised, Controlled Trial with Trazodone

Behavioural troubles due to frontotemporal dementia (FTD) are difficult to treat. The serotonergic system is associated with frontal lobes, the degeneration of which contributes to FTD. Trazodone increases the extracellular 5-HT levels in the frontal cortex. In a randomised, double-blind, placebo-co...

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Bibliographic Details
Published in:Dementia and Geriatric Cognitive Disorders 2004, Vol.17 (4), p.355-359
Main Authors: Lebert, Florence, Stekke, Willy, Hasenbroekx, Christine, Pasquier, Florence
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Agitation
Cortex
Cross-Over Studies
Dementia
Dementia - drug therapy
Dementia - psychology
Disorders
Double-Blind Method
Eating disorders
Female
Frontal lobes
Frontotemporal
Humans
Irritability
Male
Mental depression
Mental disorders
Middle Aged
Mini-Mental State Examination
Neuropsychological Tests
Patients
Personality Inventory
Placebo effect
Psychiatry
Serotonin Uptake Inhibitors - adverse effects
Serotonin Uptake Inhibitors - therapeutic use
Symptoms
Trazodone - adverse effects
Trazodone - therapeutic use
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