Neurological Complications Resulting from Non-Oral Occupational Methanol Poisoning

Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an...

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Bibliographic Details
Published in:Journal of Korean medical science 2017, 32(2), 224, pp.371-376
Main Authors: Choi, Ji Hyun, Lee, Seung Keun, Gil, Young Eun, Ryu, Jia, Jung-Choi, Kyunghee, Kim, Hyunjoo, Choi, Jun Young, Park, Sun Ah, Lee, Hyang Woon, Yun, Ji Young
Format: Article
Language:English
Subjects:
Acidosis - diagnosis
Acidosis - etiology
Adult
Ataxia - diagnosis
Ataxia - etiology
Brain - diagnostic imaging
Brief Communication
Female
Humans
Male
Methanol - poisoning
Occupational Exposure
Optic Atrophy - diagnosis
Optic Atrophy - etiology
Parkinsonian Disorders - diagnosis
Parkinsonian Disorders - etiology
Republic of Korea
Tomography, Optical Coherence
의학일반
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Summary:Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an outbreak of methanol poisoning via non-oral exposure that resulted in severe neurological complications to a few workers at industrial sites in Korea. We present 3 patients who had severe neurological complications resulting from non-oral occupational methanol poisoning. Even though initial metabolic acidosis and mental changes were improved with hemodialysis, all of the 3 patients presented optic atrophy and ataxia or parkinsonism as neurological complications resulting from methanol poisoning. In order to manage it adequately, as well as to prevent it, physicians should recognize that methanol poisoning by non-oral exposure can cause neurologic complications.
ISSN:1011-8934
1598-6357
DOI:10.3346/jkms.2017.32.2.371