Acute kidney injury and continuous renal replacement therapy in children; what pediatricians need to know

Acute kidney injury (AKI) is abrupt deterioration of renal function, and its diagnosis relies upon creatinine measurements and urine output. AKI is associated with higher morbidity and mortality, and is a risk factor of development of chronic kidney disease. There is no proven medication for AKI. Th...

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Bibliographic Details
Published in:Clinical and experimental pediatrics 2018, 61(11), , pp.339-347
Main Authors: Cho, Myung Hyun, Kang, Hee Gyung
Format: Article
Language:English
Subjects:
Acidosis
Acute kidney injury
Cell cycle
Child
Contrast agents
Creatinine
Diabetes
Disease prevention
Drug dosages
Hypotension
Infections
Kidney diseases
Metabolism
Nonsteroidal anti-inflammatory drugs
Patients
Renal replacement therapy
Review
Risk factors
Sepsis
Surgery
Ventilators
소아과학
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Summary:Acute kidney injury (AKI) is abrupt deterioration of renal function, and its diagnosis relies upon creatinine measurements and urine output. AKI is associated with higher morbidity and mortality, and is a risk factor of development of chronic kidney disease. There is no proven medication for AKI. Therefore prevention and early detection are important. Physicians need to be aware of the risk factors for AKI, and monitor renal function in high risk patients. AKI management includes optimization of volume status and renal perfusion, avoidance of nephrotoxic agents, and sufficient nutritional support. Continuous renal replacement therapy becomes widely available for critically ill children, and of which basic knowledge is introduced in this review. It is recommended that the patients who had experienced AKI are followed for renal function, blood pressure, and proteinuria for a long time.
ISSN:1738-1061
2092-7258
2713-4148
DOI:10.3345/kjp.2018.06996