Microwave Ablation of Porcine Kidneys in vivo: Effect of two Different Ablation Modes (“Temperature Control” and “Power Control”) on Procedural Outcome

• Published in: Cardiovascular and interventional radiology 2012-06, Vol.35 (3), p.653-660
• Main Authors: Sommer, C. M., Arnegger, F., Koch, V., Pap, B., Holzschuh, M., Bellemann, N., Gehrig, T., Senft, J., Nickel, F., Mogler, C., Zelzer, S., Meinzer, H. P., Stampfl, U., Kauczor, H. U., Radeleff, B. A.
• Format: Article
• Language: English
• Subjects: ABLATION; ANIMALS; BODY; Cardiology; Catheter Ablation - instrumentation; Catheter Ablation - methods; CONTROL; DOMESTIC ANIMALS; ELECTROMAGNETIC RADIATION; Imaging; IN VIVO; Kidney - surgery; KIDNEYS; Laboratory Investigation; MAMMALS; Medicine; Medicine & Public Health; MICROWAVE RADIATION; Microwaves - therapeutic use; Models, Animal; Nephrectomy - instrumentation; Nephrectomy - methods; Nuclear Medicine; ORGANS; RADIATIONS; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; SWINE; Temperature; TEMPERATURE CONTROL; Ultrasound; VERTEBRATES
• ISSN: 0174-1551; 1432-086X
• DOI: 10.1007/s00270-011-0171-5

Purpose This study was designed to analyze the effect of two different ablation modes (“temperature control” and “power control”) of a microwave system on procedural outcome in porcine kidneys in vivo. Methods A commercially available microwave system (Avecure Microwave Generator; MedWaves, San Diego, CA) was used. The system offers the possibility to ablate with two different ablation modes: temperature control and power control. Thirty-two microwave ablations were performed in 16 kidneys of 8 pigs. In each animal, one kidney was ablated twice by applying temperature control (ablation duration set point at 60 s, ablation temperature set point at 96°C, automatic power set point; group I). The other kidney was ablated twice by applying power control (ablation duration set point at 60 s, ablation temperature set point at 96°C, ablation power set point at 24 W; group II). Procedural outcome was analyzed: (1) technical success (e.g., system failures, duration of the ablation cycle), and (2) ablation geometry (e.g., long axis diameter, short axis diameter, and circularity). Results System failures occurred in 0% in group I and 13% in group II. Duration of the ablation cycle was 60 ± 0 s in group I and 102 ± 21 s in group II. Long axis diameter was 20.3 ± 4.6 mm in group I and 19.8 ± 3.5 mm in group II (not significant (NS)). Short axis diameter was 10.3 ± 2 mm in group I and 10.5 ± 2.4 mm in group II (NS). Circularity was 0.5 ± 0.1 in group I and 0.5 ± 0.1 in group II (NS). Conclusions Microwave ablations performed with temperature control showed fewer system failures and were finished faster. Both ablation modes demonstrated no significant differences with respect to ablation geometry.