Prostate Zonal Volumetry as a Predictor of Clinical Outcomes for Prostate Artery Embolization

Purpose To determine prostate baseline zonal volumetry and correlate these findings with clinical outcomes for patients who underwent prostate artery embolization (PAE) for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Materials and Methods This is a retrospective st...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2017-02, Vol.40 (2), p.245-251
Main Authors: de Assis, André Moreira, Maciel, Macello Sampaio, Moreira, Airton Mota, de Paula Rodrigues, Vanessa Cristina, Antunes, Alberto Azoubel, Srougi, Miguel, Cerri, Giovanni Guido, Carnevale, Francisco Cesar
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
ARTERIES
Cardiology
Clinical Investigation
Clinical outcomes
COMPARATIVE EVALUATIONS
Embolization, Therapeutic - methods
Follow-Up Studies
Humans
Imaging
Lower Urinary Tract Symptoms - etiology
Lower Urinary Tract Symptoms - therapy
Male
Medicine
Medicine & Public Health
Middle Aged
NMR IMAGING
Nuclear Medicine
Organ Size
PATIENTS
PROSTATE
Prostate - blood supply
Prostate - pathology
Prostatic Hyperplasia - complications
Quality of Life
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
Retrospective Studies
SYMPTOMS
Treatment Outcome
Ultrasound
URINARY TRACT
VASCULAR DISEASES
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Summary:Purpose To determine prostate baseline zonal volumetry and correlate these findings with clinical outcomes for patients who underwent prostate artery embolization (PAE) for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Materials and Methods This is a retrospective study that included patients treated by PAE from 2010 to 2014. Baseline and 6-month follow-up evaluations included prostate MRI with whole prostate (WP) and central gland (CG) volume measurements—as well as prostate zonal volumetry index (ZVi) calculation, defined as the CG/WP volumes relation—the International Prostate Symptom Score (IPSS), and the Quality of life (QoL) index. Baseline WP, CG, and ZVi were statistical compared to IPSS and QoL values at 6 months. Results A total of 93 consecutive patients were included, with mean age of 63.4 years (range, 51–86). Clinical failure, defined as IPSS > 7 or QoL > 2, was seen in four cases (4.3%). Mean reductions in prostate volumes after PAE were of 30.6% and 31.2% for WP and CG, respectively ( p  
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-016-1518-8