Direct Injection of Blood Products Versus Gelatin Sponge as a Technique for Local Hemostasis

Purpose To provide a method of reducing risk of minimally invasive procedures on patients with abnormal hemostasis and evaluate efficacy of direct fresh frozen plasma injection through a procedure needle tract compared to Gelfoam (gelatin sponge) administration. Materials and Methods Eighty patients...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2017-02, Vol.40 (2), p.231-235
Main Authors: Haaga, John, Rahim, Shiraz
Format: Article
Language:English
Subjects:
Animals
BIOMEDICAL RADIOGRAPHY
BLOOD
Blood Transfusion - methods
Cardiology
Clinical Investigation
Female
FIBRIN
GELATIN
Gelatin Sponge, Absorbable - administration & dosage
Gelatin Sponge, Absorbable - therapeutic use
HAZARDS
HEMATOMAS
HEMOGLOBIN
Hemorrhage - therapy
Hemostasis
Humans
Imaging
INJECTION
Injections
LOSSES
Male
Medicine
Medicine & Public Health
Middle Aged
Nuclear Medicine
PATIENTS
Plasma
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
Retrospective Studies
Ultrasound
VASCULAR DISEASES
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Summary:Purpose To provide a method of reducing risk of minimally invasive procedures on patients with abnormal hemostasis and evaluate efficacy of direct fresh frozen plasma injection through a procedure needle tract compared to Gelfoam (gelatin sponge) administration. Materials and Methods Eighty patients with elevated international standardized ratio (INR) undergoing minimally invasive procedures using imaging guidance were selected retrospectively. Forty patients had received Gelfoam as a means of tract embolization during the procedure. The other 40 received local fresh frozen plasma (FFP) through the needle tract. The number of complications and clinically significant bleeding events were recorded. A threshold of 30 cc of blood loss after a procedure was used to identify excess bleeding. Results No patients experienced clinically significant bleeding after administration of FFP. Five patients experienced postoperative drops in hemoglobin or hematomas after administration of Gelfoam. Conclusion Local injection of blood products can reduce postprocedure bleeding in patients undergoing minimally invasive procedures and provides a safe alternative to the use of synthetic fibrin plugs.
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-016-1494-z