INDUSTRIAL RISK FACTORS FOR COLORECTAL CANCER

Colorectal cancer is the second most common malignancy in the United States, and its incidence rates have sharply increased recently, especially in males. Industrial exposures, both occupational and environmental, are important colorectal cancer risk factors that are generally unrecognized by clinic...

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Bibliographic Details
Published in:International journal of health services 1990-01, Vol.20 (3), p.459-483
Main Authors: Lashner, Bret A., Epstein, Samuel S.
Format: Article
Language:English
Subjects:
560151 - Radiation Effects on Animals- Man
BODY
Cancer
CARCINOGENESIS
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - mortality
DIGESTIVE SYSTEM
DISEASES
DOCUMENT TYPES
Environmental Exposure
GASTROINTESTINAL TRACT
Humans
Incidence
INTESTINES
IONIZING RADIATIONS
LARGE INTESTINE
NEOPLASMS
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
Occupational Health Services
ORGANS
PATHOGENESIS
Public health
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RADIATIONS
RADIOINDUCTION
RECTUM
REVIEWS
Risk
RISK ASSESSMENT
Risk Factors
Section on Environmental Health Policy
United States
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Summary:Colorectal cancer is the second most common malignancy in the United States, and its incidence rates have sharply increased recently, especially in males. Industrial exposures, both occupational and environmental, are important colorectal cancer risk factors that are generally unrecognized by clinicians. Migration studies have documented that colorectal cancer is strongly associated with environmental risk factors. The causal role of occupational exposures is evidenced by a substantial literature associating specific work practices with increased colorectal cancer risks. Industrially related environmental exposures, including polluted drinking water and ionizing radiation, have also been associated with excess risks. Currently, there is a tendency to attribute colorectal cancer, largely or exclusively, to dietary and other lifestyle factors, thus neglecting these industrially related effects. Concerted efforts are needed to recognize the causal role of industrial risk factors and to encourage government and industry to reduce carcinogenic exposures. Furthermore, costeffective screening programs for high-risk population groups are critically needed to further reduce deaths from colorectal cancer.
ISSN:0020-7314
1541-4469
DOI:10.2190/4CQT-4L56-D43U-18XV