Secular Trends and Senescence of Blood Pressure in a Japanese and Yugoslavian Cohort of the Seven Countries Study

The aim of this study was to: (i) separately estimate the effects of secular trends and senescence from the blood pressure (BP) data of a cohort follow-up study, and (ii) compare cohort and population stroke mortality trends with systolic blood pressure (SBP) senescence (aging) and secular trends. T...

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Bibliographic Details
Published in:Blood pressure 2003, Vol.12 (1), p.32-39
Main Author: WONG, JULIA
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aging - physiology
Biological and medical sciences
Blood Pressure - physiology
Cardiovascular system
Cohort Studies
Follow-Up Studies
Humans
Hypertension - epidemiology
Hypertension - physiopathology
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Japan - epidemiology
Male
Medical sciences
Middle Aged
Models, Statistical
Multicenter Studies as Topic - statistics & numerical data
Prevalence
Risk Factors
Stroke - mortality
Stroke - physiopathology
Systole - physiology
Yugoslavia - epidemiology
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Summary:The aim of this study was to: (i) separately estimate the effects of secular trends and senescence from the blood pressure (BP) data of a cohort follow-up study, and (ii) compare cohort and population stroke mortality trends with systolic blood pressure (SBP) senescence (aging) and secular trends. The data for this work came from a Japanese ( n &#114 = &#114 508 men) and a Yugoslavian cohort ( n &#114 = &#114 552 men) of the Seven Countries Study. This report is restricted to one cohort of each country for reason of data availability. Our analysis showed that BP rose with age even after correcting for the secular trends. A significant difference in SBP rise with age was found between Yugoslavian and Japanese cohorts (0.8 &#114 vs 1.4 &#114 mmHg/year, p &#114 = &#114 0.0001). The secular and aging trends in SBP were significantly associated with the cohort and population stroke mortality in both cohorts. In conclusion, our results suggest that BP change with age does not result exclusively from biological aging; other factors also participate in the process. The rate of BP rise with age differs in two ethnically different populations. Difference in arterial stiffness and/or dietary salt intake between these populations may account for this observation.
ISSN:0803-7051
1651-1999
DOI:10.1080/08037050310003424