Direct and indirect assessment of γ-motor firing patterns

• Published in: Canadian journal of physiology and pharmacology 2004-08, Vol.82 (8-9), p.793-802
• Main Authors: Taylor, A, Durbaba, R, Ellaway, P H
• Format: Article
• Language: English
• Subjects: Action Potentials - physiology; Animals; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Humans; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration; Motor Neurons - physiology; Muscle, Skeletal - innervation; Muscle, Skeletal - physiology; Vertebrates: nervous system and sense organs
• ISSN: 0008-4212; 1205-7541
• DOI: 10.1139/y04-053

The study of the patterns of γ-motor activity which accompany natural contractions has been long and difficult, and has not as yet led to general agreement. In this review we have simplified matters by considering the case of locomotion in the cat only, and we have avoided discussion of the various hypotheses which have been advanced to provide general schemes of γ control for a wide range of movements. The development of the subject is shown to depend very much on devising ingenious methods applicable to reduced and intact animals. Direct recording from γ-motoneurones has only been possible in reduced preparations, whereas indirect assessment of γ activity from spindle afferent recordings was used in these and in intact animals. At this point in time, we still have no direct recordings from γ-motoneurones in normally behaving animals, but those obtained in decerebrate animals show distinct patterns of modulation for static and dynamic types with particular temporal relation to the stepping movements. The spindle recordings in intact animals potentially provide the most important information, and the problems of interpretation, which have previously caused difficulties, are beginning to be solved through the insights obtained from the reduced preparations.Key words: locomotion, gamma motoneurons, muscle spindles.