Investigations into the C-deuteriation of enol acetates derived from aryl alkyl ketones

Results are reported on the regioselective C‐deuteriation of a series of enol acetates (derived from the aryl alkyl ketones) using molecular deuterium as the D‐source and palladium‐on‐barium sulphate as the mediator. The results presented highlight potential problems associated with the deuteriation...

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Published in:Journal of labelled compounds & radiopharmaceuticals 2005-04, Vol.48 (5), p.337-352
Main Authors: Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka
Format: Article
Language:English
Subjects:
Chemistry
deuteriation
deuterium
enol acetates
Exact sciences and technology
hydrogenation
Labelled compounds chemistry
Organic chemistry
palladium and reduction
Reactivity and mechanisms
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container_end_page 352
container_issue 5
container_start_page 337
container_title Journal of labelled compounds & radiopharmaceuticals
container_volume 48
creator Buksha, Svitlana
Coumbarides, Gregory S.
Dingjan, Marco
Eames, Jason
Suggate, Michael J.
Weerasooriya, Neluka
description Results are reported on the regioselective C‐deuteriation of a series of enol acetates (derived from the aryl alkyl ketones) using molecular deuterium as the D‐source and palladium‐on‐barium sulphate as the mediator. The results presented highlight potential problems associated with the deuteriation of enol acetates. Copyright © 2005 John Wiley & Sons, Ltd.
doi_str_mv 10.1002/jlcr.928
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subjects Chemistry
deuteriation
deuterium
enol acetates
Exact sciences and technology
hydrogenation
Labelled compounds chemistry
Organic chemistry
palladium and reduction
Reactivity and mechanisms
title Investigations into the C-deuteriation of enol acetates derived from aryl alkyl ketones
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