SQUID-based simultaneous detection of NMR and biomagnetic signals at ultra-low magnetic fields

Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) at ultra-low magnetic fields (ULF, fields of /spl sim//spl mu/T) have several advantages over their counterparts at higher magnetic fields. These include narrow line widths, the possibility of novel imaging schemes such as T/sub 1...

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Bibliographic Details
Published in:IEEE transactions on applied superconductivity 2005-06, Vol.15 (2), p.635-639
Main Authors: Espy, M.A., Matlachov, A.N., Volegov, P.L., Mosher, J.C., Kraus, R.H.
Format: Article
Language:English
Subjects:
Applied sciences
Biomagnetics
Biomagnetism
Costs
Electronics
Exact sciences and technology
General (including economical and industrial fields)
Interference
low magnetic field
Magnetic field measurement
Magnetic fields
Magnetic resonance imaging
MRI
NMR
Nuclear magnetic resonance
SQUID
SQUIDs
Superconducting devices
Superconducting magnets
Superconducting quantum interference devices
Superconductivity
ULF
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Summary:Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) at ultra-low magnetic fields (ULF, fields of /spl sim//spl mu/T) have several advantages over their counterparts at higher magnetic fields. These include narrow line widths, the possibility of novel imaging schemes such as T/sub 1/ weighted images, and reduced system cost and complexity. In addition, ULF NMR/MRI with superconducting quantum interference devices (SQUIDs) is compatible with simultaneous measurements of biomagnetic signals, a capability conventional systems cannot offer. SQUID-based ULF MRI has already been demonstrated, as have measurements of simultaneous MEG and NMR at ULF. In this paper we will show simultaneous magnetocardiography (MCG) and magnetomyography (MMG) with NMR are also possible. Another compelling application of NMR/MRI at ULF is the possibility of directly measuring magnetic resonance consequences of neuronal signals. In this paper we explore simultaneous MMG/NMR and MCG/NMR for an effect on the NMR signal, in T/sub 2//sup */, that might be associated with the effects of bioelectric currents.
ISSN:1051-8223
1558-2515
DOI:10.1109/TASC.2005.849978