In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

Quercetin, a commonly occurring flavonoid and well known antioxidant, has been suggested to possess other beneficial activities. The present study investigated the possible anti-inflammatory effects of physiologically attainable quercetin concentrations. The effects of quercetin were tested in vitro...

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Bibliographic Details
Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2008-07, Vol.24 (7), p.703-710
Main Authors: Boots, Agnes W., Wilms, Lonneke C., Swennen, Els L.R., Kleinjans, Jos C.S., Bast, Aalt, Haenen, Guido R.M.M.
Format: Article
Language:English
Subjects:
Acids
Adult
anti-inflammatory activity
Anti-Inflammatory Agents
Anti-Inflammatory Agents - blood
Anti-Inflammatory Agents - pharmacology
Antioxidants
Antioxidants - metabolism
ascorbic acid
Biological and medical sciences
Blood
Cells, Cultured
Cytokines
dietary supplements
dose response
Dose-Response Relationship, Drug
drug effects
ex vivo studies
Feeding. Feeding behavior
Female
flavonoids
Free radicals
Fundamental and applied biological sciences. Psychology
Gastroenterology and Hepatology
glutathione
human nutrition
Humans
in vivo studies
Inflammation
Inflammation - blood
Interleukin-10
Interleukin-10 - blood
Intervention study
Lipopolysaccharide
Lipopolysaccharides
Lipopolysaccharides - toxicity
Male
men
metabolism
Middle Aged
nutritional intervention
Oxidative Stress
pharmacology
Quercetin
Quercetin - blood
Quercetin - pharmacology
Rodents
Sarcoidosis
Studies
Toxicity
tumor necrosis factor-alpha
Tumor Necrosis Factor-alpha - blood
Tumor Necrosis Factor-alpha - drug effects
Tumor necrosis factor-α
uric acid
Vertebrates: anatomy and physiology, studies on body, several organs or systems
women
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