Bowen's disease treated by carbon dioxide laser. A series of 44 patients

Background: Bowen's disease is a common form of intraepidermal (in situ) squamous cell carcinoma of the skin and mucous membrane. Treatment with destruction of the epidermis by any method is necessary to prevent invasive squamous cell carcinoma. Objective: To report our experience with CO2 lase...

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Bibliographic Details
Published in:The Journal of dermatological treatment 2008, Vol.19 (5), p.293-299
Main Authors: Covadonga Martínez-González, M., Del Pozo, Jesús, Paradela, Sabela, Fernández-Jorge, Beatriz, Fernández-Torres, Rosa, Fonseca, Eduardo
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Bowen's disease
Bowen's Disease - surgery
carbon dioxide laser
Cohort Studies
dermatologic surgery
Dermatology
Dyskeratosis
epidermal vaporization
Female
Humans
Laser Therapy
Lasers, Gas - therapeutic use
Male
Medical sciences
Middle Aged
Other treatments
Retrospective Studies
Skin Neoplasms - surgery
squamous cell carcinoma
Treatment Outcome
Treatment. General aspects
Tumors
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:Background: Bowen's disease is a common form of intraepidermal (in situ) squamous cell carcinoma of the skin and mucous membrane. Treatment with destruction of the epidermis by any method is necessary to prevent invasive squamous cell carcinoma. Objective: To report our experience with CO2 laser vaporization in the treatment of Bowen's disease and try to identify which factors could have any influence on results. Methods: A total of 44 patients were treated with the CO2 laser in superpulsed mode, focalized at 2 W cm2. Results: In 86.3% of patients, a unique treatment session was required. 'Clearance after one treatment' was achieved in 86.3% of the total series of patients and only 7.9% of these patients developed recurrence of the lesion. In 11.3% of the cases, there was 'clearance after more than one treatment' without clinical recurrences in any of these patients during the follow-up. 'No response' was achieved in 2.2% of the total series of patients. Conclusion: We conclude that the CO2 laser in superpulsed mode is an effective, efficient, safe, functional and good cosmetics treatment for Bowen's disease and it provides the same recurrence rate as other more aggressive or more expensive modalities of treatment.
ISSN:0954-6634
1471-1753
DOI:10.1080/09546630701870772