Comparison of intravenous general anaesthesia vs endotracheal intubation in the surgical management of juvenile onset recurrent respiratory papillomatosis

• Published in: Acta oto-laryngologica 2010-02, Vol.130 (2), p.281-285
• Main Authors: Lei, Wenbin, Wen, Weiping, Su, Zhenzhong, Chai, Liping, Feng, Xia, Liu, Kexuan, Jiang, Aiyun, Zhu, Xiaolin
• Format: Article
• Language: English
• Subjects: Adolescent; anaesthetic techniques; Anesthesia; Anesthesia, General - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anesthetics, Intravenous - administration & dosage; Biological and medical sciences; Child; Child, Preschool; Debridement - methods; Dyspnea - epidemiology; Endoscope; Female; General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation; Humans; Intubation, Intratracheal - methods; laryngeal microdebrider; Larynx; Male; Medical sciences; Otorhinolaryngologic Surgical Procedures - methods; Otorhinolaryngology. Stomatology; Papilloma - epidemiology; Papilloma - surgery; Recurrence; self-retained laryngoscope
• ISSN: 0001-6489; 1651-2251
• DOI: 10.3109/00016480903051643

Abstract Conclusions: Both intravenous general anaesthesia (IVGA) and general anaesthesia with endotracheal intubation (GA with ET) are applicable for the procedure of juvenile onset recurrent respiratory papillomatosis (JO-RRP). GA with ET was found to be better for JO-RRP patients with dyspnoea, as it provided better stabilization of the vital signs with fewer postoperative complications. Objectives: To evaluate the safety and efficacy of two different anaesthetic techniques in the removal of JO-RRP. Methods: A total of 52 JO-RRP patients with mild dyspnoea were included in the study. Each case underwent two procedures, one by IVGA and the other by GA with ET. A total of 104 procedures were performed. The effectiveness and safety of the two anaesthetic techniques were pairwise compared. Results: There were no significant differences in anaesthetic recovery time, operative time or postoperative voice quality between the two anaesthetic groups. However, significant differences in heart rate, oxygen saturation and carbon dioxide saturation were observed. Some patients who underwent IVGA developed apnoea (28.8%) and laryngeal spasm (19.2%). These complications were not observed in the GA with ET group.