Health services for Buruli ulcer control: lessons from a field study in Ghana

• Published in: PLoS neglected tropical diseases 2011-06, Vol.5 (6), p.e1187
• Main Authors: Ackumey, Mercy M, Kwakye-Maclean, Cynthia, Ampadu, Edwin O, de Savigny, Don, Weiss, Mitchell G
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Antibiotics; Buruli ulcer; Buruli Ulcer - diagnosis; Buruli Ulcer - drug therapy; Care and treatment; Case management; Child; Community medicine; Diagnosis; Disease; Disease prevention; Education; Environmental factors; Female; Focus groups; Ghana; Health care; Health education; Health services; Health Services Administration - statistics & numerical data; Health Services Research; Humans; Infections; Male; Medicine; Middle Aged; Mycobacterium ulcerans - isolation & purification; Public health administration; Tropical diseases; Tuberculosis; Ulcers; Young Adult
• ISSN: 1935-2735; 1935-2727; 1935-2735
• DOI: 10.1371/journal.pntd.0001187

Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, is a debilitating disease of the skin and underlying tissue. The first phase of a BU prevention and treatment programme (BUPaT) was initiated from 2005-2008, in the Ga-West and Ga-South municipalities in Ghana to increase access to BU treatment and to improve early case detection and case management. This paper assesses achievements of the BUPaT programme and lessons learnt. It also considers the impact of the programme on broader interests of the health system. A mixed-methods approach included patients' records review, review of programme reports, a stakeholder forum, key informant interviews, focus group discussions, clinic visits and observations. Extensive collaboration existed across all levels, (national, municipality, and community), thus strengthening the health system. The programme enhanced capacities of all stakeholders in various aspects of health services delivery and demonstrated the importance of health education and community-based surveillance to create awareness and encourage early treatment. A patient database was also created using recommended World Health Organisation (WHO) forms which showed that 297 patients were treated from 2005-2008. The proportion of patients requiring only antibiotic treatment, introduced in the course of the programme, was highest in the last year (35.4% in the first, 23.5% in the second and 42.5% in the third year). Early antibiotic treatment prevented recurrences which was consistent with programme aims. To improve early case management of BU, strengthening existing clinics to increase access to antibiotic therapy is critical. Intensifying health education and surveillance would ultimately increase early reporting and treatment for all cases. Further research is needed to explain the role of environmental factors for BU contagion. Programme strategies reported in our study: collaboration among stakeholders, health education, community surveillance and regular antibiotic treatment can be adopted for any BU-endemic area in Ghana.