Hemispheric asymmetries in speech perception: sense, nonsense and modulations

• Published in: PloS one 2011-09, Vol.6 (9), p.e24672-e24672
• Main Authors: Rosen, Stuart, Wise, Richard J S, Chadha, Shabneet, Conway, Eleanor-Jayne, Scott, Sophie K
• Format: Article
• Language: English
• Subjects: Acoustic noise; Acoustic properties; Acoustic Stimulation; Acoustics; Adult; Amplitude (Acoustics); Auditory Cortex - physiology; Auditory Perception - physiology; Biology; Brain; Brain Mapping; Cerebrum; Complexity; Evoked Potentials, Auditory - physiology; Excitation spectra; Female; Formants; Frequency; Hearing loss; Hemispheric laterality; Humans; Information processing; Intelligibility; Language; Language processing; Linguistics; Macaca fuscata; Male; Middle Aged; Natural language processing; Neuroimaging; Neurosciences; Noise; Phonetics; Positron emission; Positron emission tomography; Positron emission tomography (PET); Positron-Emission Tomography - methods; Psychology; Science; Sentences; Social and Behavioral Sciences; Specialization; Speech; Speech - physiology; Speech Intelligibility - physiology; Speech perception; Speech Perception - physiology; Temporal lobe; Temporal Lobe - physiology; Temporal processing; Temporal variations; Time Factors; Tomography
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0024672

The well-established left hemisphere specialisation for language processing has long been claimed to be based on a low-level auditory specialization for specific acoustic features in speech, particularly regarding 'rapid temporal processing'. A novel analysis/synthesis technique was used to construct a variety of sounds based on simple sentences which could be manipulated in spectro-temporal complexity, and whether they were intelligible or not. All sounds consisted of two noise-excited spectral prominences (based on the lower two formants in the original speech) which could be static or varying in frequency and/or amplitude independently. Dynamically varying both acoustic features based on the same sentence led to intelligible speech but when either or both acoustic features were static, the stimuli were not intelligible. Using the frequency dynamics from one sentence with the amplitude dynamics of another led to unintelligible sounds of comparable spectro-temporal complexity to the intelligible ones. Positron emission tomography (PET) was used to compare which brain regions were active when participants listened to the different sounds. Neural activity to spectral and amplitude modulations sufficient to support speech intelligibility (without actually being intelligible) was seen bilaterally, with a right temporal lobe dominance. A left dominant response was seen only to intelligible sounds. It thus appears that the left hemisphere specialisation for speech is based on the linguistic properties of utterances, not on particular acoustic features.