Longitudinal associations between adolescent psychotic experiences and depressive symptoms

Psychotic experiences are prevalent in community samples and are highly correlated with depressive symptoms. This study aimed to investigate the longitudinal associations between psychotic experiences and depressive symptoms between adolescence and young adulthood. Prospective cohort study with a 6...

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Bibliographic Details
Published in:PloS one 2014-08, Vol.9 (8), p.e105758-e105758
Main Authors: Sullivan, Sarah A, Wiles, Nicola, Kounali, Daphne, Lewis, Glyn, Heron, Jon, Cannon, Mary, Mahedy, Liam, Jones, Peter B, Stochl, Jan, Zammit, Stan
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Adults
Child
Communities
Correlation analysis
Depression - complications
Depression - epidemiology
Depression - physiopathology
Depression - psychology
Depression, Mental
Epidemiology
Female
Follow-Up Studies
Humans
Longitudinal studies
Male
Medicine and Health Sciences
Mental depression
Moods
Phenotype
Phenotypes
Physical Sciences
Pregnancy
Prospective Studies
Psychological aspects
Psychopathology
Psychotic Disorders - complications
Psychotic Disorders - epidemiology
Psychotic Disorders - physiopathology
Psychotic Disorders - psychology
Regression Analysis
Research and Analysis Methods
Studies
Surveys and Questionnaires
Teenagers
United Kingdom - epidemiology
Young adults
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Summary:Psychotic experiences are prevalent in community samples and are highly correlated with depressive symptoms. This study aimed to investigate the longitudinal associations between psychotic experiences and depressive symptoms between adolescence and young adulthood. Prospective cohort study with a 6 year follow-up in a community sample of 7632 adolescents and young adults. Depressive symptoms were assessed with the Short Moods and Feelings Questionnaire and psychotic experiences with a semi-structured clinical interview at 12 and 18 years. Longitudinal and cross-sectional associations were investigated with regression and structural equation models. Depressive symptoms and psychotic experiences were associated at each time-point (12 years r = 0.486 [95% CI 0.457, 0.515]; 18 years r = 0.286 [95% CI 0.233, 0.339]) and there were longitudinal within-phenotype associations (depressive symptoms r = 0.252 [95% CI 0.205, 0.299]; psychotic experiences r = 0.662 [95% CI 0.595, 0.729]). There was an across-phenotype association between psychotic experiences at 12 and depressive symptoms at 18 r = 0.139 [95% CI 0.086, 0.192; p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0105758