Optimal optic nerve sheath diameter threshold for the identification of elevated opening pressure on lumbar puncture in a Chinese population

Ultrasonography of the optic nerve sheath diameter (ONSD) is a non-invasive and rapid method that might be helpful in the identification of increased intracranial pressure (ICP). The use of an ONSD greater than 5 mm on ultrasound as an indicator of increased ICP in a Caucasian population has been st...

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Bibliographic Details
Published in:PloS one 2015-02, Vol.10 (2), p.e0117939-e0117939
Main Authors: Wang, Lijuan, Feng, Liangshu, Yao, Yan, Wang, Yuzhi, Chen, Ying, Feng, Jiachun, Xing, Yingqi
Format: Article
Language:English
Subjects:
Adult
Asian Continental Ancestry Group
Bacterial infections
Body mass
Body mass index
Body size
Care and treatment
Cross-Sectional Studies
Diagnosis
Emergency medical care
Female
Health aspects
Health care
Humans
Hypertension
Infections
Intensive care
Intracranial Hypertension - physiopathology
Intracranial pressure
Intracranial Pressure - physiology
Lumbar puncture
Male
Medical imaging
Medicine
Myelin Sheath - physiology
Neurology
Neurosciences
NMR
Nuclear magnetic resonance
Optic nerve
Optic Nerve - physiology
Optic nerve diseases
Patients
Population (statistical)
Population studies
ROC Curve
Sensitivity and Specificity
Spinal Cord - physiology
Spinal Puncture - methods
Studies
Systematic review
Ultrasonic imaging
Ultrasound
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Summary:Ultrasonography of the optic nerve sheath diameter (ONSD) is a non-invasive and rapid method that might be helpful in the identification of increased intracranial pressure (ICP). The use of an ONSD greater than 5 mm on ultrasound as an indicator of increased ICP in a Caucasian population has been studied. However, the cut-off point of this predictor in Chinese patients has not been established. Thus, we conducted this study to identify the ONSD criterion for the detection of elevated opening pressure on lumbar puncture (LP) in a Chinese population and to investigate the influencing factors. This study was a blind cross-sectional study. Patients who presented with suspected increased ICP were included. The opening pressure on LP of each participant was confirmed. We analyzed the clinical differences between the groups of patients with abnormal and normal opening pressures on LP. A receiver operating characteristic curve was constructed to determine the ONSD cut-off point for the identification of abnormal opening pressure on LP. In total, 279 patients were recruited, and 101 patients presented with elevated opening pressure on LP. ONSD was a significant independent predictor of elevated opening pressure on LP (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0117939