The Effect of Vascular Endothelial Growth Factor on Osteoclastogenesis in Rheumatoid Arthritis

Vascular endothelial growth factor (VEGF) has angiogenic, inflammatory, and bone-destructive roles in rheumatoid arthritis (RA). We aimed to determine the unique role of VEGF in osteoclastogenesis in RA. VEGF-induced receptor activator of nuclear factor ҡB ligand (RANKL) expression was determined in...

Full description

Saved in:

Bibliographic Details
Published in:	PloS one 2015-04, Vol.10 (4), p.e0124909
Main Authors:	Kim, Hae-Rim, Kim, Kyoung-Woon, Kim, Bo-Mi, Cho, Mi-La, Lee, Sang-Heon
Format:	Article
Language:	English
Subjects:	Acid phosphatase Acid phosphatase (tartrate-resistant) Acid resistance Angiogenesis Arthritis Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Autoimmune diseases Biocompatibility Cell Differentiation - drug effects Enzyme-linked immunosorbent assay Female Fibroblasts Fibroblasts - drug effects Fibroblasts - pathology Gene Expression Regulation - drug effects Humans Inflammation Inhibition Intracellular Space - drug effects Intracellular Space - metabolism Luciferase Male MAP kinase Middle Aged Monocytes Monocytes - drug effects Monocytes - pathology Osteoclastogenesis Osteoclasts Osteoclasts - drug effects Osteoclasts - metabolism Osteoclasts - pathology Osteoprogenitor cells Pathways Peripheral blood Plasmids Protein kinase C RANK Ligand - genetics Receptors Rheumatoid arthritis Rheumatoid factor Signal Transduction - drug effects Src protein Synovial fluid Synovial Fluid - drug effects Synovial Fluid - metabolism TRANCE protein Vascular endothelial growth factor Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - pharmacology Vascular endothelial growth factor receptors
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!