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Invasive Group B Streptococcal Disease in South Africa: Importance of Surveillance Methodology

Data on neonatal group B streptococcal (GBS) invasive disease burden are needed to refine prevention policies. Differences in surveillance methods and investigating for cases can lead to varying disease burden estimates. We compared the findings of laboratory-based passive surveillance for GBS disea...

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Bibliographic Details
Published in:PloS one 2016-04, Vol.11 (4), p.e0152524-e0152524
Main Authors: Quan, Vanessa, Verani, Jennifer R, Cohen, Cheryl, von Gottberg, Anne, Meiring, Susan, Cutland, Clare L, Schrag, Stephanie J, Madhi, Shabir A
Format: Article
Language:English
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Summary:Data on neonatal group B streptococcal (GBS) invasive disease burden are needed to refine prevention policies. Differences in surveillance methods and investigating for cases can lead to varying disease burden estimates. We compared the findings of laboratory-based passive surveillance for GBS disease across South Africa, and for one of the provinces compared this to a real-time, systematic, clinical surveillance in a population-defined region in Johannesburg, Soweto. Passive surveillance identified a total of 799 early-onset disease (EOD,
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0152524