Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU

Hemorrhagic shock remains one of the most common causes of death in severely injured patients. It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients. We retrospectively analyzed prospectively recorded data from the TraumaRegister...

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Published in:PloS one 2016-11, Vol.11 (11), p.e0148736-e0148736
Main Authors: Debus, Florian, Lefering, Rolf, Lechler, Philipp, Schwarting, Tim, Bockmann, Benjamin, Strasser, Erwin, Mand, Carsten, Ruchholtz, Steffen, Frink, Michael
Format: Article
Language:English
Subjects:
Adult
Biology and Life Sciences
Blood
Blood Banks
Blood cells
Blood Transfusion
Blood transfusions
Care and treatment
Critical care
Data processing
Documentation
Emergency medical care
Emergency medical services
Erythrocytes
Fatalities
Female
Hemorrhage
Hospitals
Humans
Injuries
Injury analysis
Injury Severity Score
Intensive care
Laboratories
Male
Medical care quality
Medical prognosis
Medicine
Medicine and Health Sciences
Middle Aged
Mortality
Patient Admission
Patient outcomes
Patients
People and Places
Quality standards
Retrospective Studies
Shock
Shock, Hemorrhagic - therapy
Studies
Therapy
Transfusion
Trauma
Trauma centers
Treatment Outcome
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cited_by cdi_FETCH-LOGICAL-c762t-c4e7d66ed906b0bf6942945e526683ee3c6ff74ba461d795aabb7a05b1d116333
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container_end_page e0148736
container_issue 11
container_start_page e0148736
container_title PloS one
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creator Debus, Florian
Lefering, Rolf
Lechler, Philipp
Schwarting, Tim
Bockmann, Benjamin
Strasser, Erwin
Mand, Carsten
Ruchholtz, Steffen
Frink, Michael
description Hemorrhagic shock remains one of the most common causes of death in severely injured patients. It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients. We retrospectively analyzed prospectively recorded data from the TraumaRegister DGU® and the TraumaNetzwerk DGU®. Inclusion criteria were Injury Severity Score (ISS) ≥ 16, primarily treated patients, and hospital admission 2 years before or after the audit process. Complete data sets of 18,573 patients were analyzed. Of 457 hospitals included, 33.3% had an in-house blood bank. In trauma centers with a blood bank (HospBB), packed red blood cells (PRBCs) (21.0% vs. 17.4%, p < 0.001) and fresh frozen plasma (FFP) (13.9% vs. 10.2%, p
doi_str_mv 10.1371/journal.pone.0148736
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It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients. We retrospectively analyzed prospectively recorded data from the TraumaRegister DGU® and the TraumaNetzwerk DGU®. Inclusion criteria were Injury Severity Score (ISS) ≥ 16, primarily treated patients, and hospital admission 2 years before or after the audit process. Complete data sets of 18,573 patients were analyzed. Of 457 hospitals included, 33.3% had an in-house blood bank. In trauma centers with a blood bank (HospBB), packed red blood cells (PRBCs) (21.0% vs. 17.4%, p &lt; 0.001) and fresh frozen plasma (FFP) (13.9% vs. 10.2%, p &lt;0.001) were transfused significantly more often than in hospitals without a blood bank (Hosp0). However, no significant difference was found for in-hospital mortality (standard mortality ratio [SMR, 0.907 vs. 0.945; p = 0.25). 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source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central
subjects Adult
Biology and Life Sciences
Blood
Blood Banks
Blood cells
Blood Transfusion
Blood transfusions
Care and treatment
Critical care
Data processing
Documentation
Emergency medical care
Emergency medical services
Erythrocytes
Fatalities
Female
Hemorrhage
Hospitals
Humans
Injuries
Injury analysis
Injury Severity Score
Intensive care
Laboratories
Male
Medical care quality
Medical prognosis
Medicine
Medicine and Health Sciences
Middle Aged
Mortality
Patient Admission
Patient outcomes
Patients
People and Places
Quality standards
Retrospective Studies
Shock
Shock, Hemorrhagic - therapy
Studies
Therapy
Transfusion
Trauma
Trauma centers
Treatment Outcome
title Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU
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