Obstetrician's risk perception on the prescription of magnesium sulfate in severe preeclampsia and eclampsia: A qualitative study in Brazil

• Published in: PloS one 2017-03, Vol.12 (3), p.e0172602
• Main Authors: Lotufo, Fátima Aparecida, Parpinelli, Mary Angela, Osis, Maria José, Surita, Fernanda Garanhani, Costa, Maria Laura, Cecatti, José Guilherme
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Attitude of Health Personnel; Biology and Life Sciences; Brazil; Care and treatment; Childbirth & labor; Data collection; Dosage and administration; Drug therapy; Drugs; Eclampsia; Eclampsia - drug therapy; Emergency medical care; Fear; Female; Gynecology; Health care; Hospitals; Humans; International organizations; Interviews; Magnesium; Magnesium sulfate; Magnesium Sulfate - therapeutic use; Male; Maternal mortality; Medical personnel; Medicine and Health Sciences; Middle Aged; Obstetricians; Obstetrics; Outcome and process assessment (Medical care); Perception; Physical Sciences; Physicians; Practice; Pre-eclampsia; Pre-Eclampsia - drug therapy; Preeclampsia; Pregnancy; Primary care; Qualitative research; Risk; Risk perception; Safety and security measures; Seizures; Skill learning; Social Sciences; Studies; Sulfates; Toxicity; Training; Womens health; Workforce; Working conditions
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0172602

Magnesium sulfate (MgSO4) is the drug of choice for the prevention and control of seizures in the management of severe preeclampsia/eclampsia. Several barriers have been identified in the use of MgSO4, especially in low and middle-income settings. To describe the obstetrician's perception on possible reasons for underutilizing magnesium sulfate to treat preeclampsia/eclampsia. A qualitative clinical study, based on phenomenological reference by semi-structured interviews and open-ended discussions with obstetricians of the public healthcare system in primary care units (PCU) and referral maternity hospitals (RMH), in a southeastern Brazilian city. Fear of drug toxicity was the major cause for not prescribing the medication in PCU. Fear was justified by insufficient technical, structural and organizational resources of healthcare facilities and by a shortage of physicians properly trained for adequate drug use. Fear of toxicity of magnesium sulfate was the main barrier towards timely and proper drug use. Periodic skill development and training of obstetricians, along with integration of the medical team in the work environment may contribute to decrease fear, ensuring safety of drug prescription and thus possibly reducing adverse outcomes related to PE.