Prevalence of psychotic disorders and its association with methodological issues. A systematic review and meta-analyses

The purpose of this study is to provide an updated systematic review to identify studies describing the prevalence of psychosis in order to explore methodological factors that could account for the variation in prevalence estimates. Studies with original data related to the prevalence of psychosis (...

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Bibliographic Details
Published in:PloS one 2018-04, Vol.13 (4), p.e0195687-e0195687
Main Authors: Moreno-Küstner, Berta, Martín, Carlos, Pastor, Loly
Format: Article
Language:English
Subjects:
Analysis
Citations
Diagnosis
Disease
Disorders
Epidemiologic Studies
Epidemiology
Estimates
Humans
Mathematical analysis
Medical diagnosis
Medicine and Health Sciences
Mental disorders
Meta-analysis
Methods
People and places
Physical Sciences
Prevalence
Prevalence studies (Epidemiology)
Psychiatry
Psychosis
Psychotic disorders
Psychotic Disorders - epidemiology
Regression analysis
Research and Analysis Methods
Reviews
Schizophrenia
Social services
Studies
Systematic review
Upgrading
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Items that cite this one
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Summary:The purpose of this study is to provide an updated systematic review to identify studies describing the prevalence of psychosis in order to explore methodological factors that could account for the variation in prevalence estimates. Studies with original data related to the prevalence of psychosis (published between 1990 and 2015) were identified via searching electronic databases and reviewing manual citations. Prevalence estimates were sorted according to prevalence type (point, 12-months and lifetime). The independent association between key methodological variables and the mean effect of prevalence was examined (prevalence type, case-finding setting, method of confirming diagnosis, international classification of diseases, diagnosis category, and study quality) by meta-analytical techniques and random-effects meta-regression. Seventy-three primary studies were included, providing a total of 101 estimates of prevalence rates of psychosis. Across these studies, the pooled median point and 12-month prevalence for persons was 3.89 and 4.03 per 1000 respectively; and the median lifetime prevalence was 7.49 per 1000. The result of the random-effects meta-regression analysis revealed a significant effect for the prevalence type, with higher rates of lifetime prevalence than 12-month prevalence (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0195687