How to combat emerging artemisinin resistance: Lessons from "The Three Little Pigs"

It is rare to come across an Aesop's fable in respectable journals. It might catch scientists outside the malaria field by surprise to learn that the famous story of "The Boy Who Cried Wolf" has been repeatedly compared to the threat from artemisinin-resistant malaria parasites, inclu...

Full description

Saved in:
Bibliographic Details
Published in:PLoS pathogens 2018-04, Vol.14 (4), p.e1006923-e1006923
Main Author: Chookajorn, Thanat
Format: Article
Language:English
Subjects:
Antimicrobial agents
Artemisinin
Biology and Life Sciences
Care and treatment
Children
Comparative analysis
Drug resistance
Health risks
Hogs
Internet
Laboratories
Malaria
Medicine
Medicine and Health Sciences
Methods
Mutation
Parasites
Pearls
Plasmodium
Plasmodium falciparum
Public health
Vector-borne diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is rare to come across an Aesop's fable in respectable journals. It might catch scientists outside the malaria field by surprise to learn that the famous story of "The Boy Who Cried Wolf" has been repeatedly compared to the threat from artemisinin-resistant malaria parasites, including the two latest reports on the rise of a specific haplotype in Cambodia and Thailand, sensationally dubbed "Super Malaria" by the media [1, 2]. The comparison to a children's tale should not negate the fact that malaria drug resistance is one of the most pressing threats to the global public health community. Here, the findings leading to this contentious discourse will be delineated in order to provide a perspective. Possible solutions will be presented to stimulate further research and discussion to solve one of the greatest public health challenges of our lifetime.
ISSN:1553-7374
1553-7366
1553-7374
DOI:10.1371/journal.ppat.1006923