Toward the 2020 goal of soil-transmitted helminthiasis control and elimination

[...]without a strategic transition plan in place, communities that used to benefit from lymphatic filariasis control activities run the risk of undermining the gains already made for soil-transmitted helminthiasis control once GPELF is discontinued. [...]the Committee welcomes the recent approval o...

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Published in:PLoS neglected tropical diseases 2018-08, Vol.12 (8), p.e0006606
Main Authors: Becker, Sören L, Liwanag, Harvy Joy, Snyder, Jedidiah S, Akogun, Oladele, Belizario, Jr, Vicente, Freeman, Matthew C, Gyorkos, Theresa W, Imtiaz, Rubina, Keiser, Jennifer, Krolewiecki, Alejandro, Levecke, Bruno, Mwandawiro, Charles, Pullan, Rachel L, Addiss, David G, Utzinger, Jürg
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Language:English
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Summary:[...]without a strategic transition plan in place, communities that used to benefit from lymphatic filariasis control activities run the risk of undermining the gains already made for soil-transmitted helminthiasis control once GPELF is discontinued. [...]the Committee welcomes the recent approval of a new, rapidly disintegrating chewable formulation of mebendazole. [...]as for other chronic infections (e.g., tuberculosis, human immune deficiency virus [HIV], and malaria), combination therapy against soil-transmitted helminthiasis might decrease this risk and could enhance efficacy [25]. [...]the need for combination therapy is further supported by coendemicity of multiple helminth infections. [...]there is a need to develop a new survey design that (1) is sufficiently powered to assess if the prevalence of moderate- or heavy-intensity infections falls below 1% and (2) is feasible and affordable, considering the limited resources and capacity of national soil-transmitted helminthiasis control programs.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0006606