Effects of hunger on mood and affect reactivity to monetary reward in women with obesity - A pilot study

• Published in: PloS one 2020-05, Vol.15 (5), p.e0232813
• Main Authors: Piccolo, Mayron, Milos, Gabriella, Bluemel, Sena, Schumacher, Sonja, Müller-Pfeiffer, Christoph, Fried, Michael, Ernst, Monique, Martin-Soelch, Chantal
• Format: Article
• Language: English
• Subjects: Adult; Affect - physiology; Biology and Life Sciences; Body Mass Index; Body weight; Complications and side effects; Dependent variables; Disabilities; Diseases; Eating disorders; Emotions; Etiology; Etiology (Medicine); Fasting; Fasting - physiology; Fasting - psychology; Female; Food; Food - adverse effects; Gastroenterology; Health aspects; Health care; Health psychology; Hepatology; Hospitals; Humans; Hunger; Hunger - physiology; Hyperphagia; Medicine and Health Sciences; Mental disorders; Mental Disorders - physiopathology; Mental Disorders - psychology; Metabolic disorders; Middle Aged; Mood; Mood (Psychology); Neurosciences; Obesity; Obesity - physiopathology; Obesity - psychology; Overweight; Overweight - physiopathology; Overweight - psychology; Pilot Projects; Population; Psychiatry; Psychological aspects; Psychosomatic medicine; Reactivity; Reinforcement; Research and Analysis Methods; Reward; Rewards (Psychology); Risk factors; Satiety; Social Sciences; Studies; Time; Women; Women's health; Womens health
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0232813

Worldwide, nearly 3 million people die every year because of being overweight or obese. Although obesity is a metabolic disease, behavioral aspects are important in its etiology. Hunger changes the rewarding potential of food in normal-weight controls. In obesity, impairments related to reward processing are present, but it is not clear whether these are due to mental disorders more common among this population. Therefore, in this pilot study, we aimed at investigating whether fasting influence mood reactivity to reward in people with obesity. Women with obesity (n = 11, all mentally healthy) and normal weight controls (n = 17) were compared on a computerized monetary reward task (the wheel of fortune), using self-reports of mood and affect (e.g., PANAS and mood evaluation during the task) as dependent variables. This task was done in 2 satiety conditions, during fasting and after eating. Partially, in line with our expectation of a reduced affect and mood reactivity to monetary reward in participants with obesity accentuated by fasting, our results indicated a significant within-group difference across time (before and after the task), with monetary gains significantly improving positive affect in healthy controls (p>0.001), but not in individuals with obesity (p = 0.32). There were no significant between-group differences in positive affect before (p = 0.328) and after (p = 0.70) the task. In addition, women with obesity, compared to controls, reported more negative affect in general (p < 0.05) and less mood reactivity during the task in response to risky gains (p < 0.001) than healthy controls. The latter was independent of the level of satiety. These preliminary results suggest an impairment in mood reactivity to monetary reward in women with obesity which is not connected to the fasting state. Increasing the reinforcing potential of rewards other than food in obesity may be one target of intervention in order to verify if that could reduce overeating.