Factors associated with insufficient weight gain among Mexican pregnant women with HIV infection receiving antiretroviral therapy

• Published in: PloS one 2020-05, Vol.15 (5), p.e0233487-e0233487
• Main Authors: Godínez, Estela, Chávez-Courtois, Mayra, Figueroa, Ricardo, Morales, Rosa María, Ramírez, Cristina, Tolentino, Maricruz
• Format: Article
• Language: English
• Subjects: Adequacy; Age; Antiretroviral agents; Antiretroviral drugs; Antiretroviral therapy; Biology and Life Sciences; Blood tests; Body mass; Body mass index; Body size; Body weight; Body weight gain; Body weight loss; CD4 antigen; Complications and side effects; Confidence intervals; Data collection; Demographic aspects; Diet; Dietary supplements; Drug therapy; Energy; Energy intake; Folic acid; Food; Food and nutrition; Food intake; Gastrointestinal symptoms; Gestational age; Health aspects; Hemoglobin; Highly active antiretroviral therapy; HIV; HIV infections; HIV patients; Human immunodeficiency virus; Infections; Lipids; Mathematical analysis; Medical records; Medicine and Health Sciences; Obesity; Obstetrics; Overweight; Perinatal infection; Population studies; Pregnancy; Pregnant women; Social class; Social factors; Socioeconomic data; Socioeconomic factors; Socioeconomics; Viruses; Weight gain; Weight loss; Womens health
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0233487

We identified clinical, dietary, and socioeconomic factors associated with insufficient gestational weight gain among Mexican pregnant women with human immunodeficiency virus (HIV) infection. This was a cross-sectional study involving 112 pregnant women with HIV infection receiving antiretroviral therapy (ART). Data including viral load, complete blood analysis, and CD4 counts were extracted from medical records. An inquiry form was used to collect data on socioeconomic status and frequency of food intake. Pre-gestational weight was calculated based on pregnancy weight to obtain the body mass index (BMI) and weight gain for gestational age according the US Institute of Medicine. Of the study population, 68.7% were in consensual union, 31.3% were single, and 33.9% belonged to the two lowest socioeconomic strata. The median age and CD4 count were 27 (interquartile range [IQR]: 23-32) years and 418 (IQR: 267-591), respectively. The adequacy of energy was 91.8% (IQR: 74.1-117.7). The median energy intake from protein was 13.5% (IQR: 12.2-14.9) and from lipids, 35.5% (IQR: 31.1-40.3). Pregnant women with gastrointestinal symptoms and CD4 count