Psychosocial impact of skin diseases: A population-based study

• Published in: PloS one 2020-12, Vol.15 (12), p.e0244765-e0244765
• Main Authors: Yew, Yik Weng, Kuan, Amanda Hui Yu, Ge, Lixia, Yap, Chun Wei, Heng, Bee Hoon
• Format: Article
• Language: English
• Subjects: Acne; Adult; Age groups; Aged; Aged, 80 and over; Arthritis; Bacterial infections; Chronic illnesses; Cross-Sectional Studies; Demographic aspects; Demographics; Dermatology; Diabetes; Disease; Evaluation; Female; Gender; Health aspects; Health services; Humans; Hypertension; Infections; Loneliness; Loneliness - psychology; Male; Medicine and Health Sciences; Mental depression; Middle Aged; Mood; Patient outcomes; People and Places; Population; Population studies; Population-based studies; Pruritus; Psoriasis; Psychological aspects; Psychology; Quality of life; Quality of Life - psychology; Regression analysis; Severity of Illness Index; Signs and symptoms; Singapore; Skin diseases; Skin Diseases - diagnosis; Skin Diseases - psychology; Social aspects; Social interactions; Social isolation; Social Isolation - psychology; Social networks; Social organization; Social Sciences; Variance analysis; Young Adult
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0244765

While it is well established that skin disease places significant psychosocial burden on a patient's wellbeing, its effects have rarely been examined in Asian populations. Evaluate the psychosocial burden of skin disease among community-dwelling adults in Singapore. This cross-sectional study included 1510 participants interviewed on their history of thirteen skin diseases. The Patient Health Questionnaire (PHQ-9), Lubben Social Network Scale-6 (LSNS-6), University of California Los Angeles (UCLA) Loneliness Scale, and European Quality of Life-5 Dimensions- 5 Level (EQ-5D-5L) were used as measures for depressive symptoms, social isolation, loneliness and quality of life respectively. Multiple linear regression analysis was used to examine the association of skin diseases with each of the four measured outcomes. Participants with skin diseases reported significantly higher PHQ-9 and UCLA Loneliness scale scores, and lower LSNS-6 and EQ-5D-5L scores when compared to their healthy counterparts. The presence of skin disease was positively associated with depressive symptoms (B = 0.40, SE = 0.11), and negatively associated with quality of life (B = -0.03, SE = 0.01). As disease severity was not evaluated in this study, we were unable to ascertain the associations between disease severity and measured outcomes. Participants with skin diseases were more likely to have depressive symptoms, social isolation, loneliness and lower quality of life. Unemployed, single and elderly patients were at higher risk of developing depressive symptoms. More emphasis should be placed on the psychosocial aspect of care to reduce the burden of skin disease. Some considerations include monitoring patients for mood-related changes and implementing early psychosocial interventions.