Effect of focused ultrasound cavitation augmented with aerobic exercise on abdominal and intrahepatic fat in patients with non-alcoholic fatty liver disease: A randomized controlled trial

The study aimed to examine the effect of focused ultrasound cavitation augmented with aerobic exercise on localized abdominal and intrahepatic fat in fatty liver patients. 34 fatty liver patients aged 30-45 with a body mass index (BMI) of 30-40 kg/m2 were randomly assigned into two equally numbered...

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Bibliographic Details
Published in:PloS one 2021-04, Vol.16 (4), p.e0250337-e0250337
Main Authors: Taha, Mona Mohamed, Aneis, Yasser M, Mohamady, Heba Mohamed, S A, Alrasheedy, Elsayed, Shereen Hamed
Format: Article
Language:English
Subjects:
Abdomen
Aerobics
Biology and Life Sciences
Body fat
Body mass
Body mass index
Body size
Body weight
Care and treatment
Cavitation
Clinical trials
Diabetes
Disease control
Exercise
Fatty liver
Geriatrics
Health aspects
Liposuction
Liver
Liver diseases
Medical imaging
Medicine and Health Sciences
Obesity
Oxidation
Physical fitness
Physical therapy
Rehabilitation
Research and Analysis Methods
Spleen
Steroids
Teaching hospitals
Tomography
Ultrasonic imaging
Ultrasound
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Summary:The study aimed to examine the effect of focused ultrasound cavitation augmented with aerobic exercise on localized abdominal and intrahepatic fat in fatty liver patients. 34 fatty liver patients aged 30-45 with a body mass index (BMI) of 30-40 kg/m2 were randomly assigned into two equally numbered groups. Group A received focused ultrasound cavitation and moderate aerobic exercise for three months, while Group B (control group) received moderate aerobic exercise only. Abdominal subcutaneous fat volume, visceral fat volume, liver-to-spleen ratio (L/S ratio), body weight, BMI, and waist circumference were measured both before and after the study period. Both groups showed significant improvements in subcutaneous fat volume, visceral fat volume, body weight, BMI, and waist circumference relative to baseline where (P < 0.001), with a higher percentage in group A. L/S ratio only showed a significant improvement in group A. Between-group differences were noteworthy regarding L/S ratio and waist circumference where (P < 0.0001). While substantial risky measures in non-alcoholic fatty liver disease have been modified by aerobic exercise, its combination with focused ultrasound cavitation causes more notable effects on the reduction of abdominal and intrahepatic fat, making it a superior option. ClinicalTrials.gov: NCT04161703.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0250337