Prevalence of sarcopenia among Saudis and its association with lifestyle behaviors: Protocol for cross-sectional study

• Published in: PloS one 2022-08, Vol.17 (8), p.e0271672-e0271672
• Main Authors: Alghannam, Abdullah F, Almasud, Alaa A, Alghnam, Suliman A, Alharbi, Dalal S, Aljubairi, Mohanad S, Altalhi, Arwa S, Jan, Azad M, Alothman, Shaima A
• Format: Article
• Language: English
• Subjects: Accelerometers; Adults; Age; Age groups; Bioelectricity; Biology and Life Sciences; Blood pressure; Cross-sectional studies; Diagnosis; Diet; Dietary intake; Dual energy X-ray absorptiometry; Etiology; Exercise; Fatigue tests; Food intake; Glucose; Health aspects; Laboratories; Life style; Lifestyles; Medicine and Health Sciences; Muscle contraction; Muscle strength; Muscular diseases; Musculoskeletal system; Nutrition; Older people; Physical activity; Population; Quality assessment; Quality of life; Questionnaires; Risk factors; Sarcopenia; Sedentary behavior; Sleep; Social Sciences; Sociodemographics; Study Protocol; Working groups; Young adults
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0271672

Sarcopenia is an age-related muscular disease manifesting as a loss of muscle function and mass-leads to detrimental consequences at both individual and community levels. Modifiable lifestyle factors (such as physical behaviors and nutritional habits) may be involved in sarcopenia etiology. European Working Group on Sarcopenia in Older Population (EWGOSP2) established a cut-off point for sarcopenia diagnosis based on the European population and they recommend the use of a regional normative population. However, no sufficient data on sarcopenia prevalence is presently available in Saudi Arabia. Therefore, this project aims to define appropriate reference values from healthy Saudi young adults (Phase I) and to investigate the prevalence of sarcopenia in Saudi Arabia (Phase II) and examine selected modifiable lifestyle correlates of sarcopenia (Phase I, II). The project will involve two phases. Phase I will include 1532 healthy Saudi young adults aged between 20-40 years. While, Phase II will include 1532 Saudi older adults aged [greater than or equal to]50 years. The study will measure vital signs, anthropometrics, muscle mass using bioelectrical impedance analysis and dual-energy X-ray absorptiometry, muscle strength using handgrip strength and maximal isometric strength, physical function using short physical performance battery, and 6-minute walk test to measure aerobic endurance. To explore the associations between lifestyle behaviors with sarcopenia indices, physical activity, sedentary behaviour and sleep will be evaluated subjectively using Global Physical Activity Questionnaire and Pittsburgh Sleep Quality Index and objectively via ActivPAL accelerometers. A three-day dietary food record will also be used to evaluate dietary intake. Additionally, EuroQOL five-dimension questionnaire will be utilized to assess health-related quality of life. The study will have significant implications in recognizing the prevalence of sarcopenia in Saudi population, which will guide our future interventional studies aimed at early prevention and treatment of this disease.