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Prescription of oral antidiabetics in Mexico. A cross-sectional study
In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors as...
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Published in: | PloS one 2023-07, Vol.18 (7), p.e0288699-e0288699 |
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description | In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico. A retrospective cross-sectional drug utilization study has been conducted. A randomly selected sample was carefully examined. Out of 3600 clinical records of patients diagnosed with type 2 diabetes mellitus (T2DM), 196 records were revised. As far as control is concerned, 36.7% had their glycemia values in the recommended range. A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause. |
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A cross-sectional study</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Fierro, Inmaculada ; Gallardo-Mora, Osiel ; Alba-Leonel, Adela ; Carvajal, Alfonso ; Molina-Guarneros, Juan Arcadio</creator><creatorcontrib>Fierro, Inmaculada ; Gallardo-Mora, Osiel ; Alba-Leonel, Adela ; Carvajal, Alfonso ; Molina-Guarneros, Juan Arcadio</creatorcontrib><description>In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico. A retrospective cross-sectional drug utilization study has been conducted. A randomly selected sample was carefully examined. Out of 3600 clinical records of patients diagnosed with type 2 diabetes mellitus (T2DM), 196 records were revised. As far as control is concerned, 36.7% had their glycemia values in the recommended range. A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0288699</identifier><identifier>PMID: 37498817</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Antidiabetics ; Biology and Life Sciences ; Blood glucose ; Body mass index ; Committees ; Complications and side effects ; Contraindications ; Cross-Sectional Studies ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - drug therapy ; Diabetes Mellitus, Type 2 - epidemiology ; Diagnosis ; Dosage and administration ; Drug Prescriptions ; Drugs ; Epidemics ; Ethics ; Evaluation ; Hospitals ; Humans ; Hypoglycemic agents ; Hypoglycemic Agents - therapeutic use ; Insulin ; Medicine and Health Sciences ; Metformin ; Mexico - epidemiology ; Morbidity ; Mortality ; Nutrition assessment ; Obesity ; Overweight ; Patient outcomes ; Patients ; People and places ; Population ; Prescription drugs ; Prescription writing ; Retrospective Studies ; Type 2 diabetes ; Womens health</subject><ispartof>PloS one, 2023-07, Vol.18 (7), p.e0288699-e0288699</ispartof><rights>Copyright: © 2023 Fierro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Fierro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Fierro et al 2023 Fierro et al</rights><rights>2023 Fierro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c509t-6418c6eb8b18abf2f6da5f8924959ea423f7ae38ecdfb27e9556737bd8f65b033</cites><orcidid>0000-0003-4423-4493</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2842935481/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2842935481?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37498817$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fierro, Inmaculada</creatorcontrib><creatorcontrib>Gallardo-Mora, Osiel</creatorcontrib><creatorcontrib>Alba-Leonel, Adela</creatorcontrib><creatorcontrib>Carvajal, Alfonso</creatorcontrib><creatorcontrib>Molina-Guarneros, Juan Arcadio</creatorcontrib><title>Prescription of oral antidiabetics in Mexico. A cross-sectional study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico. A retrospective cross-sectional drug utilization study has been conducted. A randomly selected sample was carefully examined. Out of 3600 clinical records of patients diagnosed with type 2 diabetes mellitus (T2DM), 196 records were revised. As far as control is concerned, 36.7% had their glycemia values in the recommended range. A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause.</description><subject>Age</subject><subject>Antidiabetics</subject><subject>Biology and Life Sciences</subject><subject>Blood glucose</subject><subject>Body mass index</subject><subject>Committees</subject><subject>Complications and side effects</subject><subject>Contraindications</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diagnosis</subject><subject>Dosage and administration</subject><subject>Drug Prescriptions</subject><subject>Drugs</subject><subject>Epidemics</subject><subject>Ethics</subject><subject>Evaluation</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypoglycemic agents</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>Insulin</subject><subject>Medicine and Health Sciences</subject><subject>Metformin</subject><subject>Mexico - epidemiology</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Nutrition assessment</subject><subject>Obesity</subject><subject>Overweight</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>People and places</subject><subject>Population</subject><subject>Prescription drugs</subject><subject>Prescription writing</subject><subject>Retrospective Studies</subject><subject>Type 2 diabetes</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNqFkl1rFDEUhgdRbK3-A9EBQfRi1nxMvq5kKVULlYpftyGTObObMpusSUbaf-9Md1p2RfAqgTzvOSfveYviOUYLTAV-dxWG6E2_2AYPC0Sk5Eo9KI6xoqTiBNGHe_ej4klKVwgxKjl_XBxRUSspsTguzr5ESDa6bXbBl6ErQzR9aXx2rTMNZGdT6Xz5Ga6dDYtyWdoYUqoS2EkwoikP7c3T4lFn-gTP5vOk-PHh7Pvpp-ri8uP56fKisgypXPEaS8uhkQ2WpulIx1vDOqlIrZgCUxPaCQNUgm27hghQjHFBRdPKjrMGUXpSvNzV3fYh6dmBpImsiaKslngk3s_E0GygteDz-CG9jW5j4o0OxunDF-_WehV-a4yooEpNPd7MFWL4NUDKeuOShb43HsJw26xGSmCmRvTVX-i_R3q7o1amB-28DT7DdV6ZISV9_u2rXgomOeU14f9hL38esq_32DWYPq9T6IdpMekQrHfg7e4idPd2YKSnLN2Nracs6TlLo-zFvpX3orvw0D_m_8Xb</recordid><startdate>20230727</startdate><enddate>20230727</enddate><creator>Fierro, Inmaculada</creator><creator>Gallardo-Mora, Osiel</creator><creator>Alba-Leonel, Adela</creator><creator>Carvajal, Alfonso</creator><creator>Molina-Guarneros, Juan Arcadio</creator><general>Public Library of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4423-4493</orcidid></search><sort><creationdate>20230727</creationdate><title>Prescription of oral antidiabetics in Mexico. 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A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37498817</pmid><doi>10.1371/journal.pone.0288699</doi><tpages>e0288699</tpages><orcidid>https://orcid.org/0000-0003-4423-4493</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age Antidiabetics Biology and Life Sciences Blood glucose Body mass index Committees Complications and side effects Contraindications Cross-Sectional Studies Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - epidemiology Diagnosis Dosage and administration Drug Prescriptions Drugs Epidemics Ethics Evaluation Hospitals Humans Hypoglycemic agents Hypoglycemic Agents - therapeutic use Insulin Medicine and Health Sciences Metformin Mexico - epidemiology Morbidity Mortality Nutrition assessment Obesity Overweight Patient outcomes Patients People and places Population Prescription drugs Prescription writing Retrospective Studies Type 2 diabetes Womens health |
title | Prescription of oral antidiabetics in Mexico. A cross-sectional study |
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