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Application of referenced thermodynamic integration to Bayesian model selection

Evaluating normalising constants is important across a range of topics in statistical learning, notably Bayesian model selection. However, in many realistic problems this involves the integration of analytically intractable, high-dimensional distributions, and therefore requires the use of stochasti...

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Bibliographic Details
Published in:PloS one 2023-08, Vol.18 (8), p.e0289889-e0289889
Main Authors: Hawryluk, Iwona, Mishra, Swapnil, Flaxman, Seth, Bhatt, Samir, Mellan, Thomas A
Format: Article
Language:English
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Summary:Evaluating normalising constants is important across a range of topics in statistical learning, notably Bayesian model selection. However, in many realistic problems this involves the integration of analytically intractable, high-dimensional distributions, and therefore requires the use of stochastic methods such as thermodynamic integration (TI). In this paper we apply a simple but under-appreciated variation of the TI method, here referred to as referenced TI, which computes a single model's normalising constant in an efficient way by using a judiciously chosen reference density. The advantages of the approach and theoretical considerations are set out, along with pedagogical 1 and 2D examples. The approach is shown to be useful in practice when applied to a real problem -to perform model selection for a semi-mechanistic hierarchical Bayesian model of COVID-19 transmission in South Korea involving the integration of a 200D density.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0289889