The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California

The objective of this study was to identify the prevalence and correlates of phosphatidylethanol (PEth) levels suggestive of unhealthy alcohol use among women living with and without HIV who self-reported no or low-risk drinking. We analyzed data from a cross-sectional study among women enrolled in...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2024-10, Vol.19 (10), p.e0308867
Main Authors: Jain, Jennifer P, Ma, Yifei, Dawson-Rose, Carol, Santos, Glenn-Milo, Han, Alvina, Price, Jennifer, Hahn, Judith A, Tien, Phyllis C
Format: Article
Language:English
Subjects:
Adult
Alanine
Alanine transaminase
Alcohol Drinking - blood
Alcohol Drinking - epidemiology
Alcohol use
Alcohol-related disorders
Alcoholism - blood
Alcoholism - epidemiology
Alcohols
Aspartate aminotransferase
Biomarkers
Biomarkers - blood
Cohort analysis
Correlation
Cross-Sectional Studies
Demographic aspects
Demography
Drinking
Drinking behavior
Epidemiology
Ethnicity
Female
Glycerophospholipids - blood
High density lipoprotein
HIV
HIV Infections - blood
HIV Infections - epidemiology
HIV patients
Human immunodeficiency virus
Humans
Hypotheses
Liver diseases
Metabolism
Metabolites
Middle Aged
Missing data
Prevalence
Regression analysis
Risk factors
San Francisco - epidemiology
Secondary schools
Self report
Sociodemographics
Testing laboratories
Variables
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this study was to identify the prevalence and correlates of phosphatidylethanol (PEth) levels suggestive of unhealthy alcohol use among women living with and without HIV who self-reported no or low-risk drinking. We analyzed data from a cross-sectional study among women enrolled in the San Francisco Bay Area site of the Women's Interagency HIV Study (WIHS). Between October 2017 and March 2018, PEth was tested from dried blood spots in 192 women enrolled in the San Francisco site of the WIHS. Using multivariable logistic regression, we identified the correlates of PEth levels suggestive of unhealthy alcohol use (>50 ng/ml) among the 168 women who reported no or low-risk drinking ( 1 (aOR = 3.10, 95% CI = 1.18-8.13), higher high-density lipoprotein levels (aOR = 1.31 per 10 mg/dL increase, 95% CI = 1.01-1.70), and consuming a greater number of drinks per week in the past six months (aOR = 1.40, 95% CI = 1.10-1.78). Nearly a third of women in this study had PEth levels suggestive of unhealthy alcohol use and potentially under-reported their use. To optimize alcohol related health care, there is a need to consider approaches to improve ascertainment of unhealthy alcohol use, especially among Black/African American women and those living with liver disease, so that interventions can be initiated.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0308867