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Resting-State Networks in the Infant Brain
In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as system-wide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is current...
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| Published in: | Proceedings of the National Academy of Sciences - PNAS 2007-09, Vol.104 (39), p.15531-15536 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c684t-6593856202eada23a77007b553b659fa09157406acb2277bb0453264f85b22513 |
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| cites | cdi_FETCH-LOGICAL-c684t-6593856202eada23a77007b553b659fa09157406acb2277bb0453264f85b22513 |
| container_end_page | 15536 |
| container_issue | 39 |
| container_start_page | 15531 |
| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 104 |
| creator | Fransson, Peter Skiöld, Beatrice Horsch, Sandra Nordell, Anders Blennow, Mats Lagercrantz, Hugo Åden, Ulrika |
| description | In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as system-wide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is currently unknown. Therefore, we used functional MRI to map patterns of resting-state activity in infants during sleep. We found five unique resting-states networks in the infant brain that encompassed the primary visual cortex, bilateral sensorimotor areas, bilateral auditory cortex, a network including the precuneus area, lateral parietal cortex, and the cerebellum as well as an anterior network that incorporated the medial and dorsolateral prefrontal cortex. These results suggest that resting-state networks driven by spontaneous signal fluctuations are present already in the infant brain. The potential link between the emergence of behavior and patterns of resting-state activity in the infant brain is discussed. |
| doi_str_mv | 10.1073/pnas.0704380104 |
| format | article |
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| fulltext | fulltext |
| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (39), p.15531-15536 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_pnas_primary_104_39_15531 |
| source | Open Access: PubMed Central; JSTOR Archival Journals and Primary Sources Collection |
| subjects | Adults Animals Auditory cortex Babies Behavior Biological Sciences Brain Brain - growth & development Brain - metabolism Brain - physiology Brain Mapping - methods Cerebral hemispheres Connectivity Datasets Female Humans Image Processing, Computer-Assisted Infant Infants Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicin och hälsovetenskap Models, Neurological Neurosciences Rest Sleep Visual cortex |
| title | Resting-State Networks in the Infant Brain |
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